An observational study in Staphylococcus Aureus, sponsored by Centre Hospitalier Universitaire de Saint Etienne. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-03-23.
Sponsored by Centre Hospitalier Universitaire de Saint Etienne · Observational
Nasal colonization with S. aureus is a risk factor for infection with this bacterium. A methodologically well conducted study of S. aureus bacteremia showed that 80% of S. aureus bacteremia with are due to the strain isolated in the nasal level. However, as part of a study coordinated by the CHU of Saint-Etienne, less than 50% of infections in prosthetic orthopedic devices have been linked to nasal carriage . Outside of exogenous infections, intestinal colonization with S. aureus could be an alternative source of endogenous infections with the waning of orthopedic surgery. In the general population, considering that about one third of the subjects were colonized with S. aureus nasal level and 1 in 5 in the intestine However the proportion of exclusive intestinal porting is not well known .
This study will analyze, among ICU patients, porting S. aureus nasal and rectal level. It will better clarify the relationship between nasal and rectal ports and the risk of developing an infection.
The adult patients hospitalized in intensive care at the University Hospital of Saint-Etienne have a multiresistant bacteria porting screening at the nose and rectum at admission and then once a week. These samples will be carried unchanged way for the study but will also be a research S Aureus
273 studies on the registry are indexed under Staphylococcal Infections; 29 are open to participants now.
This study's enrollment of 400 is above the median of 200 across 81 observational studies indexed under Staphylococcal Infections.
Browse Staphylococcal Infections studies →Centre Hospitalier Universitaire de Saint Etienne is the lead sponsor of 578 studies on the registry; 128 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients hospitalized in intensive care
Exclusion Criteria:
ICU patients with nasal and rectal bacterial samples for the presence of S Aureus
Procedure: Nasal and rectal bacterial samples
Bacterial nasal and rectal samples at admission and one weekly for the presence of S Aureus
prevalence of S. aureus colonization at rectal level
The presence of a colony of S. aureus on one of the samples
Time frame: 1 month
S. aureus strains similar to nasal and rectal level
S. aureus strains similar in molecular typing
Time frame: 1 month
Plan to share: No
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This study is completed, as verified in Mar 2016. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire de Saint Etienne