An interventional study of Physical Therapy in Frailty, sponsored by University of Chicago. Completed at 1 site in United States. Open to participants aged 60 Years and older. Per ClinicalTrials.gov, last updated 2023-04-26.
Sponsored by University of Chicago · Not applicable, Interventional, and Treatment
Frailty has been associated with poor acute and long-term outcomes after major surgery. We recently determined that nearly 70% of patients undergoing major thoracic surgery are pre-frail or frail. We are interested in assessing whether a strength training intervention for frail or pre-frail patients has an impact on surgical decision making and on surgical outcomes.
1,199 studies on the registry are indexed under Frailty; 430 are open to participants now.
This study's enrollment of 7 is below the median of 80 across 681 interventional studies indexed under Frailty.
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Of its 99 completed or terminated interventional studies of FDA-regulated products, 68 (69%) have results posted.
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Inclusion Criteria: • Age ≥60 years, • Qualified to consent for participation in a research study, •Thoracic disease that may require major surgery (major anatomic lung resection, esophagectomy, repair of giant paraesophageal hernia, chest wall resection, extended pleurectomy/decortication, thymectomy or major surgery for other mediastinal process),• No obvious contraindications to surgery (end-stage heart disease, end-stage lung disease, severe dementia, other specific comorbidity that would prevent surgery), • Ability to participate in physical therapy and an independent exercise program for frailty mitigation, •No need for induction chemotherapy or radiation therapy, • Recent evaluation including computed tomography of the chest or chest/abdomen.
Exclusion Criteria:• Age \<60 years, •Unable to provide informed consent, • No indication for major thoracic surgery, •Obvious contraindication to major thoracic surgery (end-stage heart disease, end-stage lung disease, severe dementia, other specific comorbidity that would preclude surgery),• Inability to participate in physical therapy and/or an independent home exercise for frailty mitigation, •Need for induction chemotherapy or radiation therapy
Patients will be receiving 6 weeks of an exercise program.
Other: Physical Therapy
6 weeks of an exercise program.
Reduction in the degree of frailty after strength training
Time frame: 18 months
Changes in surgeon risk assessment after strength training
Time frame: 18 months
This study is completed, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.
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University of Chicago