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Status unknownNCT02488577TAMISUpdated Sep 12, 2018

Outcomes of TAMIS-Total Mesorectal Excision Versus Transanal Loco-regional Excision for T2 Low Rectal Cancer

An interventional study of Transanal minimally invasive total mesorectal excision and transanal minimally invasive locoregional resection in Low Rectal Cancer, sponsored by Osama Mohammad Ali ElDamshety. Status unknown. Per ClinicalTrials.gov, last updated 2018-09-12.

Sponsored by Osama Mohammad Ali ElDamshety · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Sep 2018), so the status shown — last known as Enrolling by invitation — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
50
Allocation
Non-randomized
Sex
All
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Study summary

Cases with stage T2 N0 low rectal cancer will undergo either Transanal minimally invasive total mesorectal excision or transanal minimally invasive locoregional resection.

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Conditions studied

  • Low Rectal Cancer

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03

In context

Rectal Neoplasms

1,762 studies on the registry are indexed under Rectal Neoplasms; 518 are open to participants now.

This study's planned enrollment of 50 is below the median of 65 across 1,298 interventional studies indexed under Rectal Neoplasms.

Browse Rectal Neoplasms studies →

Lead sponsor

Osama Mohammad Ali ElDamshety is the lead sponsor of 3 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • T2 N0 low rectal cancer

Exclusion criteria

Exclusion Criteria:

  • patients unfit for laparoscopic resection
  • Unwilling to share in the study
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Crossover assignment
Masking
None (open label)
Enrollment
50 participants (estimated)

Study arms

  • Active comparator
    TAMIS TME

    T2 N0 Cases which undergo transanal minimally invasive total mesorectal excision.

    Procedure: Transanal minimally invasive total mesorectal excision

  • Active comparator
    TAMIS-Local

    T2 N0 Cases which will undergo transanal minimally invasive locoregional resection.

    Procedure: transanal minimally invasive locoregional resection

Interventions

  • ProcedureTransanal minimally invasive total mesorectal excision
  • Proceduretransanal minimally invasive locoregional resection
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What researchers measure

Primary outcomes

  1. Overall percent of postoperative complications.

    the over all percentage of Postoperative complications concerning Pelvis abscess, anastomosis disruption, bleeding, Fistula and continence function.

    Time frame: 30 days

Secondary outcomes

  1. Hospital stay

    Number of Days starting from the admission till discharge

    Time frame: 30 days

  2. Recurrence.

    number of local and distant recurrence

    Time frame: 2 years

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Study locations

No study locations are listed for this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Sep 12, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02488577
Lead sponsor
Osama Mohammad Ali ElDamshety
Responsible party
Osama Mohammad Ali ElDamshety (Assistant lecturer of surgical oncology., Mansoura University) — Sponsor-investigator
First posted
Jul 2, 2015
Start date
Jun 2015
Primary completion
Jun 2019 (estimated)
Completion
Oct 2019 (estimated)
Last update
Sep 12, 2018

Study contacts

Sherif Kotb, M.D., PhD.
study director · Professor of surgical oncology Mansoura university
Osama Eldamshety, PhD
principal investigator · surgical oncology Mansoura university
Adel Fathi, M.D.
principal investigator · surgical oncology Mansoura university

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Sep 2018. You cannot join it, but the record below documents what was studied.

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