CClinicalTrials.gg
CompletedNCT02485054VASCOUpdated Mar 25, 2019

A Predictive Score for the Ischemic Etiology of a Transient Visual Disturbances (VASCO)

An observational study in Vision Disorders, sponsored by Fondation Ophtalmologique Adolphe de Rothschild. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-03-25.

Sponsored by Fondation Ophtalmologique Adolphe de Rothschild · Observational

Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
403
Ages
18 Years and older
Sex
All
01

Study summary

The transient visual disturbances (TVD) are defined by a short abnormality of visual function. Their etiology may be ophthalmological, neurological non-ischemic or of ischemic origin.

The difficulty is to recognize an ischemic mechanism which imposes emergency cares.

A clinical score could help the clinician to recognize the etiology of the TVD .

02

Conditions studied

  • Vision Disorders

Browse trials for

03

In context

Vision Disorders

308 studies on the registry are indexed under Vision Disorders; 81 are open to participants now.

This study's enrollment of 403 is above the median of 125 across 84 observational studies indexed under Vision Disorders.

Browse Vision Disorders studies →

Lead sponsor

Fondation Ophtalmologique Adolphe de Rothschild is the lead sponsor of 311 studies on the registry; 77 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Adults having had a transient visual disturbance during the last 8 days and seen at the fondation ophtalmologique Adolphe de Rothschild

Inclusion criteria

  • Transient visual disturbances (i.e. less than 24 hours) during the last 8 days

Exclusion criteria

Exclusion Criteria:

-

05

Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
403 participants (actual)
Patient registry
No

Groups and cohorts

  • Eligible patients

    Adults having had a transient visual disturbance during the last 8 days, except a diplopia

    Other: Clinical, ophthalmological and neurological evaluation

Interventions

  • OtherClinical, ophthalmological and neurological evaluation

    Clinical : questionnaire about the symptoms and about the vascular risk factors Cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography

06

What researchers measure

Primary outcomes

  1. Etiology, ischemic or not, of the initial transient visual disturbance

    Clinical : questionnaire about the symptoms and about the vascular risk factors Cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.

    Time frame: 3 months

Secondary outcomes

  1. Incidence of new visual transient ischemic attacks during the 3 months of follow-up

    Clinical : questionnaire about the symptoms and about the vascular risk factors Cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.

    Time frame: 3 months

  2. Incidence of visual ischemic strokes during the 3 months of follow-up

    Clinical : questionnaire about the symptoms and about the vascular risk factors Cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.

    Time frame: 3 months

  3. Incidence of transient ischemic attacks, visual or not visual, during the 3 months of follow-up

    Clinical : questionnaire about the symptoms and about the vascular risk factors Cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.

    Time frame: 3 months

  4. Incidence of ischemic strokes, visual or not visual, during the 3 months of follow-up

    Clinical : questionnaire about the symptoms and about the vascular risk factors Cerebral MRI, MRI angiography of the supra-aortic trunks, ECG, Holter, transthoracic echocardiography, blood count, erythrocytes sedimentation rate, C reactive protein, visual field, optical coherence tomography, retinography and a new evaluation after 3 months.

    Time frame: 3 months

07

Study locations

2 sites
  • Hôpital Bichat
    Paris, 75018, France
  • Fondation ophtalmologique Adolphe de Rothschild
    Paris, 75020, France
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 25, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02485054
Lead sponsor
Fondation Ophtalmologique Adolphe de Rothschild
Responsible party
Sponsor
First posted
Jun 30, 2015
Start date
Sep 2015
Primary completion
Oct 2018
Completion
Oct 2018
Last update
Mar 25, 2019

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion