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CompletedNCT02474615Updated Jun 18, 2015

Applicability Clinic of Cement Portland Structural White in Endodontic Surgery

A Phase 1/2 interventional study of ENDODONTIC SURGERY in Mandibular Hypoplasia, sponsored by Universidade do Vale do Sapucai. Completed. Open to participants aged 18 Years to 60 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2015-06-18.

Sponsored by Universidade do Vale do Sapucai · Phase 1/2, Interventional, and Treatment

Phase
Phase 1/2
Study type
Interventional
Enrollment
12
Allocation
Randomized
Ages
18 Years to 60 Years
Sex
All
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Study summary

Thirty teeth twelve patients, two female and a male, who had persistent periradicular lesions were selected to participate in this study. The lesions were diagnosed with cone-beam computed tomography (cone-beam CT; Model i-Cat 17-19, Imaging Sciences International LLC).In patients with two teeth to be treated, a tooth was retroobturado with PBEA cement, (experiment) and another tooth was retroobturado with MTA cement (control).

There was significance for the two cements on the repair of wounds. Key words: Apicoectomy; Oral Surgery; Biocompatible Materials; Dental Cements; Translational Medical Research

Read the detailed description

Objective: to evaluate the clinical applicability of structural Portland white cement additive in retrofilling surgeries. Method: persistent apical periodontitis 30 teeth of 12 patients were diagnosed by computed tomography CT, cone beam. Each of them had from two to four compromised teeth. The endodontic surgery were performed and the teeth were retrofilling Each patient had a retrofilling tooth with cement mineral trioxide aggregate (MTA) control and other tooth with white Portland cement structural additive (PBEA) experiment. When the patient presented four teeth with injury, two were retrofilling with MTA and two Portland cement with structural white cement additive. Six months after surgery, there were new scans to evaluate the repair or not the wounds.

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Conditions studied

  • Mandibular Hypoplasia

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Keywords

  • Apicoectomy
  • Oral surgery
  • Biocompatible materials
  • Dental Cements
  • Translational Medical Research
03

In context

Micrognathism

26 studies on the registry are indexed under Micrognathism; 7 are open to participants now.

This study's enrollment of 12 is below the median of 24 across 22 interventional studies indexed under Micrognathism.

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Lead sponsor

Universidade do Vale do Sapucai is the lead sponsor of 28 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • patients were diagnosed by computed tomography CT, cone beam
  • each of them had from two to four compromised teeth

Exclusion criteria

Exclusion Criteria:

  • patients who did not return for review after six months
05

Study design

Phase
Phase 1 / Phase 2
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
12 participants (actual)

Study arms

  • Experimental
    TOOTH ENDODONTIC SURGERY - PBEA

    Endodontic surgery 15 teeth - PBEA

    Procedure: ENDODONTIC SURGERY

  • Experimental
    TOOTH ENDODONTIC SURGERY -MTA

    Endodontic surgery 15 teeth - MTA

    Procedure: ENDODONTIC SURGERY

Interventions

  • ProcedureENDODONTIC SURGERY

    ENDODONTIC SURGERY

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What researchers measure

Primary outcomes

  1. Regeneration measured by tomographers endodontic surgery

    Six months after surgery, there were new scans to evaluate the repair or not the wounds.

    Time frame: Six months after surgery

07

Study locations

No study locations are listed for this record.

08

References and documents

Publications

  • da Silva SR, da Silva Neto JD, Veiga DF, Schnaider TB, Ferreira LM. Portland cement versus MTA as a root-end filling material. A pilot study. Acta Cir Bras. 2015 Feb;30(2):160-4. doi: 10.1590/S0102-865020150020000011. PubMed 25714696 ↗
  • Silva Neto JD, Schnaider TB, Gragnani A, Paiva AP, Novo NF, Ferreira LM. Portland cement with additives in the repair of furcation perforations in dogs. Acta Cir Bras. 2012 Nov;27(11):809-14. doi: 10.1590/s0102-86502012001100011. PubMed 23117614 ↗
  • Feldman AM. Does academic culture support translational research? Clin Transl Sci. 2008 Sep;1(2):87-8. doi: 10.1111/j.1752-8062.2008.00046.x. No abstract available. PubMed 20443823 ↗
  • Silva Neto JD, Brito RH, Schnaider TB, Gragnani A, Engelman M, Ferreira LM. Root perforations treatment using mineral trioxide aggregate and Portland cements. Acta Cir Bras. 2010 Dec;25(6):479-84. doi: 10.1590/s0102-86502010000600004. PubMed 21120277 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 18, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02474615
Lead sponsor
Universidade do Vale do Sapucai
Responsible party
Sergio Ribeiro da Silva (Aplicability clinic of cement Portland structural additived white in surgery paraendodontic, Universidade do Vale do Sapucai) — Principal investigator
First posted
Jun 18, 2015
Start date
Feb 2013
Primary completion
Aug 2014
Completion
Jan 2015
Last update
Jun 18, 2015

Study contacts

Daniela Francescato Veiga
study director · BRAZIL, UNIVAS

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2015. You cannot join it, but the record below documents what was studied.

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