A Phase 2/3 interventional study of Aloe Vera in Periodontitis, sponsored by Dr. D. Y. Patil Dental College & Hospital. Completed. Open to participants aged 30 Years to 60 Years. Per ClinicalTrials.gov, last updated 2015-06-04.
Sponsored by Dr. D. Y. Patil Dental College & Hospital · Phase 2/3, Interventional, and Treatment
Background: Aloe vera is considered to be the most promising and high-ranking agent as an all-purpose herbal plant amongst herbal agents used in dentistry. This study was designed to evaluate the clinical and microbiological effectiveness of locally delivered aloe vera gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
Background: Aloe vera is considered to be the most promising and high-ranking agent as an all-purpose herbal plant amongst herbal agents used in dentistry. This study was designed to evaluate the clinical and microbiological effectiveness of locally delivered aloe vera gel as an adjunct to scaling and root planing in the treatment of chronic periodontitis.
Methods: Twelve subjects diagnosed with chronic generalized periodontitis were selected and randomly divided into two groups: Test group which received scaling and root planning (SRP) followed by application of aloe vera gel as a local drug delivery agent in the deepest periodontal pocket and control group which received SRP alone. Clinical evaluation was undertaken using Plaque index (PI), Gingival index (GI), Probing pocket depth (PPD), Relative attachment level (RAL) and Gingival marginal level (GML) and microbiologic counts (total colony count/ml) were assessed at baseline, 6 weeks and 3 months.
1,664 studies on the registry are indexed under Periodontitis; 328 are open to participants now.
This study's enrollment of 12 is below the median of 45 across 1,206 interventional studies indexed under Periodontitis.
Browse Periodontitis studies →Dr. D. Y. Patil Dental College & Hospital is the lead sponsor of 13 studies on the registry; 1 is open to participants now.
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Inclusion Criteria:
Inclusion in this study was based on the following criteria:
Exclusion Criteria:
Exclusion criteria were:
Group recieving scaling and root planing and aloe vera gel local drug delivery
Drug: Aloe Vera
Group recieving only scaling and root planing
Drug pages: Aloe vera gel · Aloe vera
Local drug delivery of aloe vera gel
Change in Relative Attachment Loss was taken as the primary outcome
Time frame: 3 months
Change in Probing depth
Time frame: 3 months
Change in number of microbial species
Time frame: 3 months
No study locations are listed for this record.
This study is completed, as verified in Jun 2015. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Aloe vera gel · Aloe vera
Dr. D. Y. Patil Dental College & Hospital