An interventional study of Virtual interactive memory training and Passive information activities in Mild Cognitive Impairment, sponsored by Ministry of Science and Technology, Taiwan. Completed at 1 site in Taiwan. Open to participants aged 65 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-12-15.
Sponsored by Ministry of Science and Technology, Taiwan · Not applicable, Interventional, and Prevention
This study sought to investigate the changes in objective memory performance (including immediate recall and delayed recall), subjective memory complaints and degree of depression in older adults with mild cognitive impairment after Virtual interactive memory training (VIMT).
This double-blind randomized controlled study has a 2-arm parallel group design. All subjects will be randomized by the block randomization, into intervention group (Virtual interactive memory training, VIMT), or active control group (Passive information activities, PIA). Training sessions of the VIMT group are 45 minutes/day, 3 days/week, for 12 weeks (36 sessions each). The training of PIA group is the same as VIMT group. We constructed a rigorous VIMT program adhering to the Consolidated Standards of Reporting Trials (CONSORT) reporting guidelines. The investigators expect to determine the improvement in memory function and degree of depression of older adults with mild cognitive impairment after using the VIMT.
Exclusion Criteria:
Training sessions of the VIMT group are divided into initial training and booster training. Each training session is 45 minutes/day, 3 sessions/week, for 12 weeks for both initial training and booster training (36 sessions each).
Behavioral: Virtual interactive memory training
The training of active control group is the same as VIMT group (45 min/day, 3 days/week, for 12 weeks, for a total of 36 sessions). The active control group receives only the initial training.
Behavioral: Passive information activities
Training sessions of the VIMT group are divided into initial training and booster training. Each training session is 45 minutes/day, 3 sessions/week, for 12 weeks for both initial training and booster training (36 sessions each). The training content of the four memory training include: (1) spatial encoding memory training task, (2) updating-spatial memory training task, (3) updating-visual memory training task, and (4) rehearsal-visuospatial memory training task.
Also known as: Memory training
The active control group (Passive information activities) only accepts the initial training phase, which training content of the two types to include: (1) listening to audio books, and (2) reading online newspaper.
Also known as: Active control group
Change in objective memory performance as measured by the Chinese version of the Wechsler Memory Scale-III (WMS-III).
Time frame: Change from baseline in objective memory performance at Immediate post-test, 3 months, 6 months and one year after intervention.
Change in subjective memory complaints as measured by the Multifactorial Memory Questionnaire (MMQ).
Time frame: Change from baseline in subjective memory complaints at Immediate post-test, 3 months, 6 months and one year after intervention.
This study is completed, as verified in Dec 2017. You cannot join it, but the record below documents what was studied.
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Ministry of Science and Technology, Taiwan