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CompletedNCT02451020Updated Oct 30, 2018

Acclimatization of Healthy Subjects During a Stay at 3200 m

An interventional study of Altitude exposure in Effects of High Altitude, sponsored by University of Zurich. Completed at 1 site in Kyrgyzstan. Open to participants aged 20 Years to 75 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2018-10-30.

Sponsored by University of Zurich · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
20 Years to 75 Years
Sex
All
01

Study summary

The study evaluates respiratory acclimatization in healthy lowlanders staying for 3 weeks at 3200 m.

Read the detailed description

This study evaluates the effect of 3 weeks altitude acclimatization on sleep related breathing disturbances in healthy subjects staying at 3200 m. Participants living in Bishkek, Kyrgyzstan (700 m), will be transferred by car within 4 h to the Tuja Ashu high altitude clinic (3200 m). Outcomes will be assessed repeatedly during the stay at 3200 m.

02

Conditions studied

  • Effects of High Altitude

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Keywords

  • healthy volunteers
  • acclimatization
  • sleep
  • hypoxia
03

In context

Altitude Sickness

189 studies on the registry are indexed under Altitude Sickness; 44 are open to participants now.

This study's enrollment of 20 is below the median of 33 across 157 interventional studies indexed under Altitude Sickness.

Browse Altitude Sickness studies →

Lead sponsor

University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Perfect health
  • Born, raised and currently living at low altitude (\<800m)
  • Informed consent.

Exclusion criteria

Exclusion Criteria:

  • Any acute or chronic disease
  • heavy smoking (>20 cigarettes per day).
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Altitude exposure

    Stay at 3200 m for 3 weeks

    Other: Altitude exposure

Interventions

  • OtherAltitude exposure

    Participants will stay for 3 weeks at an altitude of 3200 m

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What researchers measure

Primary outcomes

  1. Mean nocturnal oxygen saturation measured by pulse oximetry

    Difference in mean nocturnal oxygen saturation between night 1 and night 7

    Time frame: night 7 at 3200 m

Secondary outcomes

  1. Mean nocturnal oxygen saturation measured by pulse oximetry

    Difference in mean nocturnal oxygen saturation between night 1 at 3200 and night 1 at 700 m

    Time frame: night 1 at 3200 m

  2. Mean nocturnal oxygen saturation measured by pulse oximetry

    Difference in mean nocturnal oxygen saturation between night 21 and night 1 at 3200 m

    Time frame: night 21 at 3200 m

  3. Mean nocturnal oxygen saturation measured by pulse oximetry

    Mean nocturnal oxygen saturation during night 1 at 700 m

    Time frame: night 1 at 700 m (low altitude baseline)

07

Study locations

1 site
  • National Center of Cardiology and Internal Medicine
    Bishkek, 720040, Kyrgyzstan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 30, 2018, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02451020
Lead sponsor
University of Zurich
Collaborators
National Center of Cardiology and Internal Medicine named after academician M.Mirrakhimov
Responsible party
Sponsor
First posted
May 21, 2015
Start date
Jun 8, 2015
Primary completion
Aug 9, 2015
Completion
Aug 9, 2015
Last update
Oct 30, 2018

Study contacts

Konrad E Bloch, MD
study chair · University Hospital, Zürich
Talant M Sooronbaev, MD
study director · National Center of Cardiology and Internal Medicine, Bishkek, Kyrgyzstan

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2018. You cannot join it, but the record below documents what was studied.

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