An observational study in Pain, Postoperative, sponsored by University of Florida. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-01-19.
Sponsored by University of Florida · Observational
The purpose of this research study is to determine what causes pain after surgery to increase or decrease over time.
Before surgery, study participants will be asked questions about age, gender, race/ethnicity, annual income, and education level. Study participants will also be questioned regarding prior pain experiences, their mood and how they think about pain. A small test tube of blood, a cheek swab or a saliva sample will be taken to see what genetic differences may influence individuals pain after surgery.
After surgery, study participants will be asked questions about their pain intensity while in the hospital. Additional information will be collected about the effects of pain medicine, and their recovery from surgery.
Following discharge from the hospital, study participants will be contacted monthly to confirm continued communication. Study participants will also be contacted six months after surgery, and asked to complete a final survey about their pain after surgery.
5,089 studies on the registry are indexed under Pain, Postoperative; 1,137 are open to participants now.
This study's enrollment of 428 is above the median of 102 across 607 observational studies indexed under Pain, Postoperative.
Browse Pain, Postoperative studies →University of Florida is the lead sponsor of 1,254 studies on the registry; 201 are open to participants now.
Of its 170 completed or terminated interventional studies of FDA-regulated products, 136 (80%) have results posted.
Counted across the registry records on this site, refreshed daily.
Patients scheduled for surgery will be invited to participate in this study.
Exclusion Criteria:
Patients undergoing non-ambulatory surgery will be asked questions and complete surveys in an effort to characterize postoperative pain experience profiles. A blood sample will be obtained for genetic markers exploring a variety of pain-related genes.
Behavioral: Surgical patients' clinical progression · Genetic: Genetic markers
Study the dynamic nature of pain
Research variants in genes related to pain sensitivity, analgesic sensitivity and opioid response
Measure postoperative pain scores change with respect to time
Pain scores will be measured using previously established pain scale and Questionnaire
Time frame: up to 7 days
Measure variables that contribute to postoperative pain scores
Variables: clinical, biological, psychological, and social factors
Time frame: up to 6 months
Measure timing patterns that may influence development of persistent postsurgical pain (PPP)
Different patterns of pain analgesia-pain cycles
Time frame: up to 6 months
Genetic testing
Specific single nucleotide polymorphisms
Time frame: up to 1 day
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2021. You cannot join it, but the record below documents what was studied.
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University of Florida