An interventional study of C-reactive protein dosage in Colorectal Postoperative Complication, sponsored by Centre Hospitalier Departemental Vendee. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-04-20.
Sponsored by Centre Hospitalier Departemental Vendee · Not applicable, Interventional, and Other
Colic and rectal resection represents a majority of hospitalizations in visceral surgery. The objective of this study was to evaluate the prognostic of inflammatory markers dosage (CRP, procalcitonin and venous lactate) on the postoperative recovery after colorectal surgery and on the length of stay.
1,233 studies on the registry are indexed under Postoperative Complications; 292 are open to participants now.
This study's enrollment of 174 is above the median of 119 across 689 interventional studies indexed under Postoperative Complications.
Browse Postoperative Complications studies →Centre Hospitalier Departemental Vendee is the lead sponsor of 81 studies on the registry; 12 are open to participants now.
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Exclusion Criteria:
Other: C-reactive protein dosage
C-reactive Protein Rate
Comparison C-reactive protein levels \< 172 mg/l at 3 post operative day with composite endpoint postoperative recovery (fever, absence of pain \>2, intestinal gas transit and patient autonomy for mobility and body care) at 5 post operative day. The Specificity, Sensitivity, PPV, NPV of C-Reactive Protein Levels at Day 3 Post-operative in Determining Day 5 Post-operative Recovery
Time frame: 5 postoperative days
| Milestone | C-reactive Protein Dosage |
|---|---|
| Started | 174 |
| Completed | 168 |
| Not completed | 6 |
| Withdrew: Crp measuring missing | 5 |
| Withdrew: Unscheduled stoma | 1 |
Comparison C-reactive protein levels \< 172 mg/l at 3 post operative day with composite endpoint postoperative recovery (fever, absence of pain \>2, intestinal gas transit and patient autonomy for mobility and body care) at 5 post operative day. The Specificity, Sensitivity, PPV, NPV of C-Reactive Protein Levels at Day 3 Post-operative in Determining Day 5 Post-operative Recovery
| percentage | C-reactive Protein Dosage |
|---|---|
| Sensitivity | 47.9 (33.8 to 62.0) |
| Specificity | 81.0 (74.0 to 88.0) |
| PPV | 50.0 (35.5 to 64.4) |
| NPV | 79.5 (72.6 to 86.8) |
Collected over 3 months. Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| C-reactive Protein Dosage | 1/168 (0.6%) | 0/168 (0%) | 0/168 (0%) |
| Age, Continuous(years) | C-reactive Protein Dosage |
|---|---|
| Mean | 65.1 ± 13.2 |
| Sex: Female, Male(Participants) | C-reactive Protein Dosage |
|---|---|
| Female | 76 |
| Male | 92 |
| Race and Ethnicity Not Collected(Participants) | C-reactive Protein Dosage |
|---|
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Centre Hospitalier Departemental Vendee