An interventional study of Chewing gum in Colorectal Cancer and Surgery, sponsored by Countess of Chester NHS Foundation Trust. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2015-02-26.
Sponsored by Countess of Chester NHS Foundation Trust · Not applicable, Interventional, and Prevention
It is unknown whether post operative chewing gum will reduce post operative ileus. This study is a randomised controlled trial that will determine whether chewing gum three times a day following surgery will reduce post operative ileus. Time to passage of flatus will be used to determine that incidence of ileus.
Patients will be randomised to one of two arms, the experimental arm will be chewing gum and the control arm will be normal post operative care.
The primary endpoint is time to passage of flatus (defined as end of operation to first passage of flatus, in minutes).
The trial will be unblinded to patients and observers and has been powered to demonstrate a 15% reduction in passage to flatus (130 patients required)
5,599 studies on the registry are indexed under Colorectal Neoplasms; 1,458 are open to participants now.
This study's planned enrollment of 130 is above the median of 77 across 4,122 interventional studies indexed under Colorectal Neoplasms.
Browse Colorectal Neoplasms studies →Countess of Chester NHS Foundation Trust is the lead sponsor of 6 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Patients will chew sugar free gum three times a day
Dietary Supplement: Chewing gum
Normal post operative care
Sugar free chewing gum
Bowel function (as assessed by questionnaire)
Time to passage of flatus
Time frame: Minutes (end of surgery to first passage of flatus, measured up to 4 weeks)
Diet (as assessed by questionnaire)
Time to tolerating full diet
Time frame: Minutes (end of surgery to first solid food, assessed by patient questionnaire up to 4 weeks from randomisation)
Length of stay
Time frame: Days (till successful discharge from secondary care to home or respite care measured up to first 31 days)
Post op nausea and vomiting score (as recorded by visual analogue scale)
Post op nausea and vomiting score (PONV)
Time frame: Recorded daily for first 5 days
Morbidity
Post operative morbidity
Time frame: Days (recorded up to 30 days and defined by Clavien-Dindo scale)
This study is status unknown, as verified in Feb 2015. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Countess of Chester NHS Foundation Trust