An observational study in Surgery, sponsored by Hospital Ambroise Paré Paris. Completed at 2 sites in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-04-30.
Sponsored by Hospital Ambroise Paré Paris · Observational
The objective of these cohorts is to detect potential genetic, neurophysiological psychological and cognitive risk factors for the development of chronic postsurgical pain including neuropathic pain.
This new study will enroll patients undergoing mastectomy or thoracotomy for cancer. They will be three cohorts :
The main objectives of these cohorts will be to detect potential genetic, neurophysiological, psychological and cognitive risk factors for the development of chronic postsurgical neuropathic pain.
These patients will questioned about demographics, age, sex, body mass index. A large neuropsychological and psychological battery of tests will be conducted. Sensory function will assessed using quantitative sensory testing. Biological samples will analyse potential genetic factors in the development of neuropathic pain after surgery. Conditioned pain modulation, threshold tracking and quantitative sensory testing will also be assessed in subgroup of patients.
The prospective cohort will be assessed before surgery then 3, 6 and 12 months after surgery. The cross sectional cohort will be assessed during one to two visits in hospital.
1,287 studies on the registry are indexed under Neuralgia; 256 are open to participants now.
This study's enrollment of 250 is above the median of 100 across 260 observational studies indexed under Neuralgia.
Browse Neuralgia studies →Hospital Ambroise Paré Paris is the lead sponsor of 23 studies on the registry; 6 are open to participants now.
Counted across the registry records on this site, refreshed daily.
The first group of patients consists of women recruited from René Huguenin Hospital (Saint Cloud, Ile de France) for mastectomy or lumpectomy to treat breast cancer, with axillary lymph node dissection in all cases.
The second cohort will consist of women already operared of breast surgery in the last 2 years.
The third cohort will consist of men or women recruited from Foch hospital (Suresnes, Ile de France) for thoracotomy for cancer.
Exclusion criteria :
Prospective cohort
Cross sectional cohort
neuropathic pain
neuropathic pain assessed with the DN4 questionnaire
Time frame: 3, 6 and 12 months after surgery in the prospective cohort
chronic postsurgical pain
chronic pain questionnaire identification
Time frame: 3, 6 and 12 months after surgery
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Apr 2021. You cannot join it, but the record below documents what was studied.
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Hospital Ambroise Paré Paris