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CompletedNCT02362555Updated Nov 13, 2015

The Effect of Nuchal Ligament Calcification on Cervical Function in Patients With Neck Pain

An observational study in Neck Pain, sponsored by Changhua Christian Hospital. Completed at 1 site in Taiwan. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2015-11-13.

Sponsored by Changhua Christian Hospital · Observational

Study type
Observational
Model
Case-control
Time perspective
Cross-sectional
Enrollment
68
Ages
20 Years to 80 Years
Sex
All
01

Study summary

Ossification of nuchal ligament often observed in patient with chronic neck pain, previous study showed ossification of nuchal ligament was associated with cervical spondylosis and radiculopathy. Patient with chronic neck pain was divided into two groups according to the presence of ossification of nuchal ligament on cervical radiographic images.

This study is to evaluate and compare the neck function including range of motion, neck strength and pressure pain threshold, radiography characteristics and functional disability between two groups.

02

Conditions studied

  • Neck Pain

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Keywords

  • Ossification of nuchal ligament
03

In context

Neck Pain

1,232 studies on the registry are indexed under Neck Pain; 255 are open to participants now.

This study's enrollment of 68 is below the median of 90 across 213 observational studies indexed under Neck Pain.

Browse Neck Pain studies →

Lead sponsor

Changhua Christian Hospital is the lead sponsor of 74 studies on the registry; 10 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

patient with chronic neck pain

Inclusion criteria

  • Patient with neck pain and stiffness last for more than 1 month

Exclusion criteria

Exclusion Criteria:

  • cervical trauma or fracture in 3 months
  • evidence of cervical spine instability
  • rheumatoid cervical spondylopathy
  • previous cervical surgery
  • head and neck cancer
  • previous radiotherapy over neck and surrounding
  • those complicated with myelopathy
  • contraindication to radiography like pregnant woman
05

Study design

Observational model
Case-control
Time perspective
Cross-sectional
Enrollment
68 participants (actual)
Patient registry
No

Groups and cohorts

  • ossification of nuchal ligament

    check neck function, radiography characteristics and complete functional disability questionnaire

    Other: no intervention was used in this observational study

  • Non ossification of nuchal ligament

    check neck function, radiography characteristics and complete functional disability questionnaire

    Other: no intervention was used in this observational study

Interventions

  • Otherno intervention was used in this observational study
06

What researchers measure

Primary outcomes

  1. Degrees of cervical range of motion

    active range of motion in flexion, extension,lateral bending and rotation direction with Cervical Range of Motion (CROM) instrument

    Time frame: 1 day ( first visit)

  2. Angles of cervical lordotic curve at C2-C7 on cervical x-ray

    measured by both modified Cobb method and Harrison posterior tangent method at C2-C7 in every participants

    Time frame: within one week after first visit

  3. Scores of functional disability as a measure of effects of neck pain on daily living

    neck disability index (NDI) with 10-item scaled questionnaire

    Time frame: 1 day ( first visit)

  4. The values of neck flexor, extensor, lateral bending and rotation strength

    measured with a handheld dynamometer

    Time frame: 1 day ( first visit)

  5. The values of pressure pain threshold as a measure of participants' pain sensitivity

    Pressure gauge algometer was applied to bilateral upper trapezius

    Time frame: 1 day ( first visit)

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Study locations

1 site
  • Changhua Christian Hospital Taiwan
    Changhua, 500, Taiwan
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 13, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02362555
Lead sponsor
Changhua Christian Hospital
Responsible party
Ta-Sen Wei,MD (Director, Physical Medical and Rehabilitation, Principal Investigator, Clinical Professor, Changhua Christian Hospital) — Principal investigator
First posted
Feb 13, 2015
Start date
Apr 2014
Primary completion
Aug 2015
Completion
Aug 2015
Last update
Nov 13, 2015

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Nov 2015. You cannot join it, but the record below documents what was studied.

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