An interventional study of Slow Speed of spinal injection and Fast Speed of spinal injection in Pregnancy and Effects of; Anesthesia, Spinal and Epidural; in Pregnancy, sponsored by Ministry of Health, Malaysia. Completed at 1 site in Malaysia. Open to female participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-12-12.
Sponsored by Ministry of Health, Malaysia · Not applicable, Interventional, and Treatment
The purpose of this study is to investigate if prolonging the speed of injection during spinal anaesthesia can reduce the incidence of hypotension and/or medication requirements thereby making it safer for the mother and foetus.
We plan to investigate if by varying the speed of injection during spinal anaesthesia, will there be a difference in the incidence of hypotension. Hypotension is a common complication especially for pregnant women undergoing caesarean section. A high speed of injection can theoretically cause a higher spread of anaesthetic, which may increase the incidence of hypotension. We want to know if by prolonging the injection time, will this lead to a reduction in a rate of hypotension.
Ministry of Health, Malaysia is the lead sponsor of 27 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Slow group patients will receive spinal injection over 60 seconds. Vital signs monitored every minute after injection. Hypotension is treated with IV Phenylephrine or Ephedrine.
Procedure: Slow Speed of spinal injection
Fast group patients will receive spinal injection over 15 seconds. Vital signs monitored every minute after injection. Hypotension is treated with IV Phenylephrine or Ephedrine.
Procedure: Fast Speed of spinal injection
Speed of injection over 60 seconds
Speed of injection over 15 seconds
Incidence of Hypotension
How many patients will experience a drop in systolic Blood Pressure of greater than 20%
Time frame: First 10 minutes after injection
Use of vasoconstrictors
Time frame: First 10 minutes after injection
Adequacy of block
To determine if the anaesthetic is adequate for the surgery (no pain or movement experienced around the surgical field)
Time frame: Time of surgery
This study is completed, as verified in Dec 2014. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Ministry of Health, Malaysia