An interventional study of Tributyrin and C8-diet oil in Type 2 Diabetes, sponsored by Glostrup University Hospital, Copenhagen. Completed. Open to male participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-10-15.
Sponsored by Glostrup University Hospital, Copenhagen · Not applicable, Interventional, and Treatment
This study compared the incretin-releasing effect of C8-diet oil and tributyrin with that of 20 ml olive oil on a molar basis in human volunteers.
A structured triglyceride (1,3-di-octanoyl-2-oleoyl-glycerol, called C8-diet oil), which upon digestion results in generation of two medium-chain fatty acids and 2-oleoyl-glycerol (2-OG), may lead to activation of GPR119 only, since medium fatty acids are poor agonists for fatty acid receptors.
9,589 studies on the registry are indexed under Diabetes Mellitus, Type 2; 1,332 are open to participants now.
This study's enrollment of 12 is below the median of 81 across 7,713 interventional studies indexed under Diabetes Mellitus, Type 2.
Browse Diabetes Mellitus, Type 2 studies →Glostrup University Hospital, Copenhagen is the lead sponsor of 106 studies on the registry; 5 are open to participants now.
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Exclusion Criteria:
A meal containing 200 g grated carrot and 0.0216 mol tributyrin; blood test taken from 0 - 2 hours postprandial
Dietary Supplement: Tributyrin · Dietary Supplement: Carrot
A meal containing 200 g grated carrot and 0.0216 mol of C8-diet oil; blood test taken from 0 - 2 hours postprandial
Dietary Supplement: C8-diet oil · Dietary Supplement: Carrot
A meal containing 200 g grated carrot and 0.0216 mol of olive oil; blood test taken from 0 - 2 hours postprandial
Dietary Supplement: Olive oil · Dietary Supplement: Carrot
A meal containing 200 g grated carrot; blood test taken from 0 - 2 hours postprandial
Dietary Supplement: Carrot
a triglyceride containing three C4-acids
a triglyceride containing 2 C8-fatty acids and one oleic acid at sn-2 position
a triglyceride containing mostly three oleic acids
mainly water and glucose
plasma GLP-1
Time frame: 2 hours postprandial
plasma GIP
Time frame: 2 hours postprandial
plasma insulin
Time frame: 2 hours postprandial
plasma PYY
Time frame: 2 hours postprandial
plasma glucose
Time frame: 2 hours postprandial
plasma neurotensin
Time frame: 2 hour postprandial
plasma CCK
Time frame: 2 hour postprandial
No study locations are listed for this record.
This study is completed, as verified in Oct 2014. You cannot join it, but the record below documents what was studied.
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Studies of the drugs tested here: Tributyrin · Olive Oil
Glostrup University Hospital, Copenhagen →