An observational study in Anorexia Nervosa, sponsored by NYU Langone Health. Terminated at 1 site in United States. Open to female participants aged 18 Years to 55 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-08-17.
Sponsored by NYU Langone Health · Observational
The purpose of this study is to use positron emission tomography (PET) imaging and magnetic resonance imaging (MRI) to understand the brain function of individuals with anorexia nervosa and healthy controls.
This is a 3-year study involving n=7 women with anorexia nervosa - recovered (AN-REC) from restricting subtype that have achieved a body mass index (BMI) > 18.5 in the past year, are medication free, range in age from 18-55 years and n=7 healthy (medical and psychiatric statues) age- and weight-matched controls who are invited to participate in a medical and psychiatric evaluation, neuroendocrine assessments, one magnetic resonance imaging (MRI) study and one positron emission tomography (PET) study kappa opioid receptor (KOR) 11-carbon (11C) [11C]PKAB and PET. Subjects will be asked to provide written informed consent after full explanation of all study procedures and risks and benefits related to study participation. On the screening day a full medical evaluation including blood work, urine analyses, toxicology, electrocardiogram (ECG) and physical exam will be performed.
411 studies on the registry are indexed under Anorexia; 67 are open to participants now.
This study's enrollment of 7 is below the median of 65 across 104 observational studies indexed under Anorexia.
Browse Anorexia studies →NYU Langone Health is the lead sponsor of 1,391 studies on the registry; 254 are open to participants now.
Of its 227 completed or terminated interventional studies of FDA-regulated products, 191 (84%) have results posted.
Counted across the registry records on this site, refreshed daily.
Subjects are female, between the age range of 18 to 55, are medically healthy and currently not taking any medications to treat any medical illness, and have a history of anorexia nervosa and are recovered or never had a history of anorexia nervosa.
Inclusion criteria for anorexic patients:
Inclusion criteria for healthy controls:
Exclusion criteria for anorexic patients:
Exclusion criteria for healthy controls:
Anorexia Nervosa - Recovered (AN-REC)
Other: Positron emission tomography (PET) imaging
Healthy Control (HC)
Other: Positron emission tomography (PET) imaging
Positron emission tomography (PET) imaging
Volume of distribution (VT) (i.e., KOR binding) using [11C]PKAB and PET imaging
In this study we are using the KOR radioligand \[11C\]PKAB and PET to investigate group differences in cerebral KOR binding potential in 7 AN-REC and 7 healthy controls (HCs).
Time frame: Two months
This study is terminated, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.
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NYU Langone Health