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CompletedNCT02235142AndroCanUpdated Jan 20, 2022

Prostatic Cancer Versus Androgen Deficiency

An interventional study of Blood sample in Cancer of Prostate, sponsored by Hopital Foch. Completed at 8 sites in 3 countries. Open to male participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2022-01-20.

Sponsored by Hopital Foch · Not applicable, Interventional, and Other

From the registry’s dates

  • Registered 1 year 3 months after the study started (first participant enrolled Jun 2013, registered Sep 2014).
Phase
Not applicable
Study type
Interventional
Enrollment
1,614
Allocation
Not applicable
Ages
18 Years and older
Sex
Male
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Study summary

Open study to make a comparison between hypogonadism and euogonadism patients regarding the severity of prostate cancer. The purpose of this study is to determine the importance of the relationship between the hormonal status and the type of the tumor at the time of surgical intervention as well as follow up of the patients.

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Conditions studied

  • Cancer of Prostate

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In context

Prostatic Neoplasms

6,370 studies on the registry are indexed under Prostatic Neoplasms; 1,397 are open to participants now.

This study's enrollment of 1,614 is above the median of 58 across 4,821 interventional studies indexed under Prostatic Neoplasms.

Browse Prostatic Neoplasms studies →

Lead sponsor

Hopital Foch is the lead sponsor of 208 studies on the registry; 21 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
Male
Accepts healthy volunteers
No

Inclusion criteria

  • Male patients over than 18 years of age, with localized, stage I or II prostate cancer, not receiving local treatment (radiation, phototherapy, thermotherapy,...) or hormonal therapy, showing indication of radical prostatectomy.

Exclusion criteria

Exclusion Criteria:

  • Absence of radical prostatectomy indication
  • Patient received local or hormonal therapy prior to surgery
  • Patients already enrolled in other clinical study incompatible with the study
  • Patients on a treatment which can affect hormonal level (Prednisone, Ketoconazole, Abiraterone, Finasteride, Dutasteride)
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Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
1,614 participants (actual)

Study arms

  • Experimental
    Localised prostat cancer and androgen deficiency

    Other: Blood sample

Interventions

  • OtherBlood sample
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What researchers measure

Primary outcomes

  1. Testosteron Serum level

    Time frame: The day prior to surgery

  2. Gleason score

    Time frame: 5 years

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Study locations

8 sites
  • Hôpital Foch
    Suresnes, Ile De France 92150, France
  • Clinique Saint Augustin
    Bordeaux, 33000, France
  • Hôpitaux Civils de Colmar
    Colmar, 68000, France
  • Hôpital Henri Mondor
    Créteil, 94000, France
  • La Pitié-Salpêtrière (AP-HP)
    Paris, 75013, France
  • Institut Mutualiste Montsouris
    Paris, 75014, France
  • CHU Pointe à Pitre
    Pointe-à-Pitre, 97110, Guadeloupe
  • CHU Fort de France
    Fort-de-France, 97200, Martinique
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References and documents

Publications

  • Neuzillet Y, Raynaud JP, Dreyfus JF, Radulescu C, Rouanne M, Schneider M, Krish S, Roupret M, Drouin SJ, Comperat E, Galiano M, Cathelineau X, Validire P, Molinie V, Fiet J, Giton F, Lebret T, Botto H. Aggressiveness of Localized Prostate Cancer: the Key Value of Testosterone Deficiency Evaluated by Both Total and Bioavailable Testosterone: AndroCan Study Results. Horm Cancer. 2019 Feb;10(1):36-44. doi: 10.1007/s12672-018-0351-8. Epub 2018 Oct 6. PubMed 30293206 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 20, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02235142
Lead sponsor
Hopital Foch
Responsible party
Sponsor
First posted
Sep 9, 2014
Start date
Jun 3, 2013
Primary completion
Jun 27, 2016
Completion
Dec 22, 2021
Last update
Jan 20, 2022
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Jan 2022. You cannot join it, but the record below documents what was studied.

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