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CompletedNCT02200120Updated Jul 21, 2015

Evaluation of Catheter Placement for Renal Replacement Therapy in Patients With Acute Kidney Injury

An observational study in Acute Kidney Injury, sponsored by Brigham and Women's Hospital. Completed at 1 site in United States. Per ClinicalTrials.gov, last updated 2015-07-21.

Sponsored by Brigham and Women's Hospital · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
150
Sex
All
01

Study summary

The purpose of this study is to examine the placement, timing, associated complications, efficacy of temporary and tunneled catheters for renal replacement therapy in patient with acute kidney injury.

Read the detailed description

The purpose of this study is to examine the placement, timing, associated complications, efficacy of temporary and tunneled catheters for renal replacement therapy in patient with acute kidney injury. In particular, we will be assessing renal replacement adequacy for patients on dialysis and continuous veno-venous hemofiltration by monitoring urea reduction ratios, venous and arterial pressures. We will also be monitoring infection rates. We will compare these outcomes in patients receiving tunneled catheters and patients receiving temporary catheters.

02

Conditions studied

  • Acute Kidney Injury
03

In context

Acute Kidney Injury

1,595 studies on the registry are indexed under Acute Kidney Injury; 371 are open to participants now.

This study's enrollment of 150 is close to the median of 150 across 773 observational studies indexed under Acute Kidney Injury.

Browse Acute Kidney Injury studies →

Lead sponsor

Brigham and Women's Hospital is the lead sponsor of 1,236 studies on the registry; 224 are open to participants now.

Of its 116 completed or terminated interventional studies of FDA-regulated products, 64 (55%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients admitted to the hospital with acute kidney injury requiring renal replacement therapy

Inclusion criteria

  • Patients admitted to the hospital with acute kidney injury requiring renal replacement therapy

Exclusion criteria

Exclusion Criteria:

  • End stage renal disease
  • Chronic kidney disease 5 progression to end stage renal disease
  • Outside hospital catheter placement
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
150 participants (actual)
Patient registry
No
06

What researchers measure

Primary outcomes

  1. Dialysis adequacy

    Adequacy will be measured using urea reduction ratio for patients on intermittent hemodialysis. For continuous renal replacement therapy, we will record the maximum blood flow rate achievable. These measurements/recordings will be made on average within 1-3 days of starting therapy.

    Time frame: up to 7d after starting renal replacement therapy

Secondary outcomes

  1. blood stream infection rates

    Patients will be followed throughout their hospitalization, which can range from a few days to several weeks. Bloodstream infections within 30d of catheter placement will be recorded.

    Time frame: within 30d of catheter placement

07

Study locations

1 site
  • Brigham and Women's Hospital
    Boston, Massachusetts 02215, United States
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 21, 2015, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02200120
Lead sponsor
Brigham and Women's Hospital
Responsible party
Sushrut S Waikar (Associate Professor, Brigham and Women's Hospital) — Principal investigator
First posted
Jul 25, 2014
Start date
Jan 2013
Primary completion
Jun 2015
Completion
Jun 2015
Last update
Jul 21, 2015

Study contacts

Sushrut Waikar, MD, MHS
principal investigator · Brigham and Women's Hospital
Mallika L Mendu
study director · Brigham and Women's Hospital

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jul 2015. You cannot join it, but the record below documents what was studied.

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