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CompletedNCT02187146VIDIOUpdated Oct 25, 2016

The Effects of Serum Vitamin D and IVF Outcome

An observational study in Vitamin D Deficiency, Vitamin D Insufficiency and Infertility, sponsored by University of Birmingham. Completed at 1 site in United Kingdom. Open to female participants aged 23 Years to 43 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-10-25.

Sponsored by University of Birmingham · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
504
Ages
23 Years to 43 Years
Sex
Female
01

Study summary

The purpose of this study is to investigate whether an association exists between serum vitamin D levels and IVF treatment outcome

02

Conditions studied

  • Vitamin D Deficiency
  • Vitamin D Insufficiency
  • Infertility

Keywords

  • Vitamin D
  • Infertility
  • IVF
  • ART
03

In context

Infertility

2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.

This study's enrollment of 504 is above the median of 200 across 714 observational studies indexed under Infertility.

Browse Infertility studies →

Lead sponsor

University of Birmingham is the lead sponsor of 179 studies on the registry; 30 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
23 Years to 43 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

All patients undergoing IVF, ICSI and FET treatment cycles at the Birmingham Womens Fertility Centre

Inclusion criteria

  • All patients undergoing IVF, ICSI or FET treatment at Birmingham Womens Fertility Centre

Exclusion criteria

Exclusion Criteria:

  • None
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
504 participants (actual)
Patient registry
No

Groups and cohorts

  • ART population

    Patients undergoing IVF/ICSI/FET treatment at the Birmingham Womens Fertility Centre 2013-2014

06

What researchers measure

Primary outcomes

  1. Clinical Pregnancy Rate

    USS appearances of intrauterine pregnancy

    Time frame: 7 weeks after embryo transfer

Secondary outcomes

  1. Biochemical pregnancy rate

    Urinary pregnancy test result 2 weeks after embryo transfer

    Time frame: 2 weeks after embryo transfer

  2. Miscarriage rate

    Pregnancy outcome of miscarriage

    Time frame: 20 weeks after embryo transfer

  3. Live birth rate

    Live birth outcome

    Time frame: 42 weeks after embryo transfer

07

Study locations

1 site
  • Birmingham Womens NHS Foundation Trust
    Birmingham, West Midlands B15 2TG, United Kingdom
08

References and documents

Publications

  • Chu J, Gallos I, Tobias A, Robinson L, Kirkman-Brown J, Dhillon-Smith R, Harb H, Eapen A, Rajkhowa M, Coomarasamy A. Vitamin D and assisted reproductive treatment outcome: a prospective cohort study. Reprod Health. 2019 Jul 15;16(1):106. doi: 10.1186/s12978-019-0769-7. PubMed 31307482 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 25, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02187146
Lead sponsor
University of Birmingham
Responsible party
Justin Chu (Research Fellow, University of Birmingham) — Principal investigator
First posted
Jul 10, 2014
Start date
Sep 2013
Primary completion
Dec 2014
Completion
Dec 2015
Last update
Oct 25, 2016

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2016. You cannot join it, but the record below documents what was studied.

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