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CompletedNCT02165137Updated Mar 15, 2024

Management of Major Trauma Patients at Aarau Trauma Center - Evaluation of Processes and Patient Outcome

An observational study in Injury, Trauma and Major Trauma, sponsored by Kantonsspital Aarau. Completed at 1 site in Switzerland. Per ClinicalTrials.gov, last updated 2024-03-15.

Sponsored by Kantonsspital Aarau · Observational

Study type
Observational
Model
Cohort
Time perspective
Other
Enrollment
3,800
Sex
All
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Study summary

Quality control and improvement project: Assessment and analysis of processes and outcome in trauma emergency room and major trauma patients at the Aarau trauma center (cantonal hospital) with regard to initial emergency management, hospital processes and short- and long-term (1-and 2-year) outcome of patients (subjective and objective). Comparison of processes and outcome pre- and post- project initiative. Benchmarking with the literature and by participation in the German and Swiss Trauma registry each.

Read the detailed description

Registry of all emergency patients arriving at Aarau trauma center following trauma with regard to possibly injury related pre- and inhospital demographic factors, process variables and outcome Parameters.

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Conditions studied

  • Injury
  • Trauma
  • Major Trauma
  • Multiple Trauma

Keywords

  • trauma
  • major trauma
  • multiple trauma
  • outcome
  • quality
  • process Management
  • emergency room
  • trauma center
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In context

Wounds and Injuries

5,056 studies on the registry are indexed under Wounds and Injuries; 861 are open to participants now.

This study's enrollment of 3,800 is above the median of 135 across 1,597 observational studies indexed under Wounds and Injuries.

Browse Wounds and Injuries studies →

Lead sponsor

Kantonsspital Aarau is the lead sponsor of 27 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All emergency patients treated at Aarau Cantonal Hospital following trauma (\<24h postinjury) with suspected major trama

Inclusion criteria

  • major trauma: New Injury Severity Score (NISS) >=8
  • for longer-term outcome: only patients firm in German language and able to respond to the postal questionnaire by themselves

Exclusion criteria

Exclusion Criteria:

  • no Trauma
  • injury >24h before arrival at Aarau Cantonal Hospital
  • NISS\<8
  • for longer-term outcome: patients not firm in German language and not able to respond to the postal questionnaire by themselves (dead, unavailable, refusal to participate, dementia, age\<16 years ecc.); a categorising compilation of cases is supposed to exclude any possible study bias
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Study design

Observational model
Cohort
Time perspective
Other
Enrollment
3,800 participants (actual)
Target follow-up
2 Years
Patient registry
Yes

Groups and cohorts

  • trauma patients

    type and severity of patients, circumstances and trauma pre- and post-injury / -quality initiative

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What researchers measure

Primary outcomes

  1. emergency room process times

    Time frame: hours (<6)

Secondary outcomes

  1. hospital mortality

    Time frame: 30 days

  2. Euro Quality of Life Group health-related quality of life on five dimensions (EQ-5D)

    score

    Time frame: 1 and 2 year follow-up

  3. Trauma Outcome Profile (TOP)

    score

    Time frame: 1 and 2 year follow-up

  4. Quality of Life after Brain Injury (QOLIBRI)

    score

    Time frame: 1 and 2 year follow-up

  5. medical outcomes study Short Form-36 (SF-36)

    score

    Time frame: 1 and 2 year follow-up

  6. reduced capacity to work

    Value (%);e.g. see Gross T, Attenberger C, Huegli RW, Amsler F. Factors associated with reduced longer-term capacity to work in patients after polytrauma: a Swiss trauma center experience. J Am Coll Surg. 2010 Jul;211(1):81-91

    Time frame: 1 and 2 year outcome

Other outcomes

  1. invalidity

    % of disability to work (i.e., basis for resulting amount of insurance pension)

    Time frame: at least 4 year post-injury

  2. insurance payments

    Swiss Francs

    Time frame: at least 4 years post-injury

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Study locations

1 site
  • Aarau Cantonal Hospital
    Aarau, Aargau 5001, Switzerland
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References and documents

Publications

  • Gross T, Amsler F. Prevalence and incidence of longer term pain in survivors of polytrauma. Surgery. 2011 Nov;150(5):985-95. doi: 10.1016/j.surg.2011.04.003. Epub 2011 Jun 15. PubMed 21676423 ↗
  • Attenberger C, Amsler F, Gross T. Clinical evaluation of the Trauma Outcome Profile (TOP) in the longer-term follow-up of polytrauma patients. Injury. 2012 Sep;43(9):1566-74. doi: 10.1016/j.injury.2011.01.002. Epub 2011 Jan 20. PubMed 21255778 ↗
  • Gross T, Attenberger C, Huegli RW, Amsler F. Factors associated with reduced longer-term capacity to work in patients after polytrauma: a Swiss trauma center experience. J Am Coll Surg. 2010 Jul;211(1):81-91. doi: 10.1016/j.jamcollsurg.2010.02.042. Epub 2010 May 15. PubMed 20610253 ↗
  • Fueglistaler P, Amsler F, Schuepp M, Fueglistaler-Montali I, Attenberger C, Pargger H, Jacob AL, Gross T. Prognostic value of Sequential Organ Failure Assessment and Simplified Acute Physiology II Score compared with trauma scores in the outcome of multiple-trauma patients. Am J Surg. 2010 Aug;200(2):204-14. doi: 10.1016/j.amjsurg.2009.08.035. Epub 2010 Mar 15. PubMed 20227058 ↗
  • Fuglistaler-Montali I, Attenberger C, Fuglistaler P, Jacob AL, Amsler F, Gross T. In search of benchmarking for mortality following multiple trauma: a Swiss trauma center experience. World J Surg. 2009 Nov;33(11):2477-89. doi: 10.1007/s00268-009-0193-1. PubMed 19693630 ↗
  • Gross T, Schuepp M, Attenberger C, Pargger H, Amsler F. Outcome in polytraumatized patients with and without brain injury. Acta Anaesthesiol Scand. 2012 Oct;56(9):1163-74. doi: 10.1111/j.1399-6576.2012.02724.x. Epub 2012 Jun 26. PubMed 22735047 ↗
  • Gross T, Morell S, Scholz SM, Amsler F. The capacity of baseline patient, injury, treatment and outcome data to predict reduced capacity to work and accident insurer costs - a Swiss prospective 4-year longitudinal trauma centre evaluation. Swiss Med Wkly. 2019 Dec 17;149:w20144. doi: 10.4414/smw.2019.20144. eCollection 2019 Dec 16. PubMed 31846504 ↗
  • Gross T, Morell S, Amsler F. To What Extent Are Main Accident-Insurer Cases Representative of All Significantly Injured? A Swiss Monocenter Perspective. J Insur Med. 2019;48(1):65-78. doi: 10.17849/insm-48-1-1-14.1. Epub 2019 Apr 24. PubMed 31017516 ↗
  • Gross T, Morell S, Amsler F. Gender-Specific Improvements in Outcome 1 and 2 Years After Major Trauma. J Surg Res. 2019 Mar;235:459-469. doi: 10.1016/j.jss.2018.10.024. Epub 2018 Nov 21. PubMed 30691830 ↗
  • Gross T, Braken P, Amsler F. Trauma center need: the American College of Surgeons' definition in contrast to Swiss highly specialized medicine regulations-a Swiss trauma center perspective. Eur J Trauma Emerg Surg. 2020 Apr;46(2):397-406. doi: 10.1007/s00068-018-1027-3. Epub 2018 Oct 13. PubMed 30317378 ↗
  • Born K, Amsler F, Gross T. Prospective evaluation of the Quality of Life after Brain Injury (QOLIBRI) score: minor differences in patients with major versus no or mild traumatic brain injury at one-year follow up. Health Qual Life Outcomes. 2018 Jul 9;16(1):136. doi: 10.1186/s12955-018-0966-z. PubMed 29986710 ↗
  • Gross T, Amsler F. One-year outcome following brain injury: a comparison of younger versus elderly major trauma patients. Arch Orthop Trauma Surg. 2018 Oct;138(10):1375-1387. doi: 10.1007/s00402-018-2974-1. Epub 2018 Jun 11. PubMed 29948226 ↗
  • Gross T, Morell S, Amsler F. Longer-term quality of life following major trauma: age only significantly affects outcome after the age of 80 years. Clin Interv Aging. 2018 Apr 30;13:773-785. doi: 10.2147/CIA.S158344. eCollection 2018. PubMed 29750022 ↗
  • Braken P, Amsler F, Gross T. Simple modification of trauma mechanism alarm criteria published for the TraumaNetwork DGU(R) may significantly improve overtriage - a cross sectional study. Scand J Trauma Resusc Emerg Med. 2018 Apr 24;26(1):32. doi: 10.1186/s13049-018-0498-x. PubMed 29690930 ↗
  • Bundi M, Meier L, Amsler F, Gross T. [Impact of weather, time of day and season on the admission and outcome of major trauma patients]. Unfallchirurg. 2018 Jan;121(1):10-19. doi: 10.1007/s00113-016-0267-0. German. PubMed 27778061 ↗
  • Gross T, Amsler F. [Long-term outcome following multiple trauma in working age : A prospective study in a Swiss trauma center]. Unfallchirurg. 2016 Nov;119(11):921-928. doi: 10.1007/s00113-014-2720-2. German. PubMed 25633852 ↗
  • Gross T, Amsler F. [Emergency room and major trauma treatment is a "loss-making business" : A Swiss trauma center experience with current DRG reimbursement]. Unfallchirurg. 2021 Sep;124(9):747-754. doi: 10.1007/s00113-020-00937-w. Epub 2020 Dec 18. German. PubMed 33337516 ↗
  • Walkner S, Amsler F, Gross T. [How often is a chest tube needed following thoracic trauma in the severely injured-and when is more needed? : Data from a Swiss trauma center for planning of resources and surgical training]. Chirurg. 2021 Aug;92(8):721-728. doi: 10.1007/s00104-020-01292-7. German. PubMed 33034700 ↗
  • Gross T, Morell S, Amsler F. Medically graded reduced capacity to work (RCW) following significant injury as explained by patient related outcome measures (PROMs): A prospective trauma center evaluation. Disabil Health J. 2021 Oct;14(4):101114. doi: 10.1016/j.dhjo.2021.101114. Epub 2021 May 10. PubMed 34059469 ↗
  • Gross T, Amsler F. Main factors predicting somatic, psychological, and cognitive patient outcomes after significant injury: a pilot study of a simple prognostic tool. BJS Open. 2021 Nov 9;5(6):zrab109. doi: 10.1093/bjsopen/zrab109. PubMed 34864883 ↗
  • Zeindler M, Amsler F, Gross T. Comparative analysis of MGAP, GAP, and RISC2 as predictors of patient outcome and emergency interventional need in emergency room treatment of the injured. Eur J Trauma Emerg Surg. 2021 Dec;47(6):2017-2027. doi: 10.1007/s00068-020-01361-w. Epub 2020 Apr 13. PubMed 32285143 ↗
  • Fiumedinisi FA, Amsler F, Gross T. Short-term outcome following significant trauma: increasing age per se has only a relatively low impact. Eur J Trauma Emerg Surg. 2021 Dec;47(6):1979-1992. doi: 10.1007/s00068-020-01357-6. Epub 2020 Apr 16. PubMed 32300851 ↗
  • Magyar CTJ, Maeder F, Diepers M, Amsler F, Gross T. Detailed information gain and therapeutic impact of whole body computed tomography supplementary to conventional radiological diagnostics in blunt trauma emergency treatment: a consecutive trauma centre evaluation. Eur J Trauma Emerg Surg. 2022 Apr;48(2):921-931. doi: 10.1007/s00068-020-01502-1. Epub 2020 Sep 30. PubMed 32997166 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Mar 15, 2024, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02165137
Lead sponsor
Kantonsspital Aarau
Collaborators
Kantonsspital Aarau, Wissenschaftlicher Fond, Suva
Responsible party
Thomas Gross, MD (Prof. Dr. med., Kantonsspital Aarau) — Principal investigator
First posted
Jun 17, 2014
Start date
Jan 2010
Primary completion
Dec 2019
Completion
Dec 2020
Last update
Mar 15, 2024

Study contacts

Thomas Gross, MD, Prof.
principal investigator · Aarau Cantonal Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Mar 2024. You cannot join it, but the record below documents what was studied.

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