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CompletedNCT02150642Updated Aug 16, 2022

Probing Neural Circuitry for the Control of Movement

An observational study in Neurological Movement Disorders, sponsored by University of Zurich. Completed at 1 site in Switzerland. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2022-08-16.

Sponsored by University of Zurich · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
250
Ages
18 Years and older
Sex
All
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Study summary

The investigators are interested in examining 1) the basic organization of spinal and cortical circuitry for the control of movement and 2) the influence of injury of these circuits. To investigate the neuronal circuitry, the investigators use various types of mechanical or electrical stimulation of the limbs, transcranial magnetic stimulation of the cortex and galvanic vestibular stimulation in both uninjured human subjects and subjects with a neurological injury (such as spinal cord injury, or Parkinsons's disease).

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Conditions studied

  • Neurological Movement Disorders

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03

In context

Movement Disorders

320 studies on the registry are indexed under Movement Disorders; 98 are open to participants now.

This study's enrollment of 250 is above the median of 80 across 132 observational studies indexed under Movement Disorders.

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Lead sponsor

University of Zurich is the lead sponsor of 1,030 studies on the registry; 130 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

control subjects without neurological movement disorder AND patients with neurological movement disorder

Inclusion criteria

  • control subjects: no neurological movement disorder
  • patients: neurological movement disorder

Exclusion criteria

Exclusion Criteria:

patients and control subjects:

  • presence of any central psychiatric disorder that precludes subject from giving informed and voluntary consent
  • presence of any cardiovascular conditions or limitations that restrict the ability to walk on a treadmill continuously for more than 20 minutes
  • for the electrical stimulation examination, subjects with metal implants are also excluded
  • for the TMS and GVS examination, subjects with the following conditions are excluded: metal implants in the head, cardiac pacemakers, history of migraine headaches, history of major head injury, history of stroke, history of seizures, previous brain neurosurgery, unstable medical conditions, major psychiatric disorders, pregnancy -
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
250 participants (actual)
Patient registry
No

Groups and cohorts

  • Neurological Injury
  • No Neurological Injury
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What researchers measure

Primary outcomes

  1. Spinal reflex activity

    Spinal reflex activity will be assessed by electrical nerve stimulation

    Time frame: one day

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Study locations

1 site
  • University of Zurich
    Zurich, 8008, Switzerland
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 16, 2022, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02150642
Lead sponsor
University of Zurich
Responsible party
Sponsor
First posted
May 30, 2014
Start date
May 2004
Primary completion
Jul 31, 2020
Completion
Jul 31, 2020
Last update
Aug 16, 2022

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.

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