ClinicalTrials.gg
CompletedNCT02111733TnT-HDUpdated Apr 11, 2014

Is High Sensibility Troponins a Dialysable Marker in Hemodialysis Patients and Does it Have Prognostic Value?

An interventional study of Hs-TNT dosage in Renal Failure, sponsored by Université de Sherbrooke. Completed at 2 sites in Canada. Open to participants aged 50 Years and older. Per ClinicalTrials.gov, last updated 2014-04-11.

Sponsored by Université de Sherbrooke · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
43
Allocation
Not applicable
Ages
50 Years and older
Sex
All
01

Study summary

Evaluation of High sensibility troponin levels modification by hemodialysis in terminal renal failure patient at Sherbrooke University Hospital Center as determined by serial measurements. Verification of potential effects of these levels and their variation as predictors of cardiovascular outcomes and events at 6 and 12 months.

Read the detailed description

Recruiting of hemodialysis patients of the nephrology renal supplementation clinics at Sherbrooke University Hospital Center to measure three blood level of high-sensibility troponins before and after standard dialysis. Verification on the variation of these levels after dialysis. Follow-up at 6 and 12 months of the patient for Cardiovascular events and death and verification of a possible predictive value of troponin blood levels for these events.

02

Conditions studied

  • Renal Failure

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03

In context

Renal Insufficiency

2,030 studies on the registry are indexed under Renal Insufficiency; 168 are open to participants now.

This study's enrollment of 43 is close to the median of 43 across 1,534 interventional studies indexed under Renal Insufficiency.

Browse Renal Insufficiency studies →

Lead sponsor

Université de Sherbrooke is the lead sponsor of 296 studies on the registry; 67 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
50 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • over 50 years, no symptoms, over 1 months of hemodialysis

Exclusion criteria

Exclusion Criteria:

  • 1 or more in the last month; Acute coronary syndrome, Heart failure decompensated, Myo or Pericarditis, Pulmonary embolism, Sepsis/shock, Stroke or transient ischemic attack, Malignant high blood pressure, Arrythmia, electrical cardio-version, major trauma, significant burnings (>25%), Chemotherapy, Cardiovascular surgery, percutaneous angio-intervention,
  • Chronic systemic disease (sarcoidosis, amyloidosis, LED, Etc.)
05

Study design

Phase
Not applicable
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
43 participants (actual)

Study arms

  • Experimental
    Hs-TnT

    Hs-TNT dosage

    Other: Hs-TNT dosage

Interventions

  • OtherHs-TNT dosage

    Bloodwork before and after hemodialysis for high sensibility troponins T blood level

06

What researchers measure

Primary outcomes

  1. High sensibility troponins T blood level variation

    Verification of high sensibility troponins T blood after classical hemodialysis compared to pre-treatment levels.

    Time frame: 1 week

Secondary outcomes

  1. Prognostic value of high sensibility troponins T blood level variation

    Evaluation of a potential prognosis value of high sensibility troponins T blood levels and its variation after hemodialysis.

    Time frame: at 6 and 12 months

07

Study locations

2 sites
  • Centre hospitalier universitaire de Sherbrooke
    Sherbrooke, Quebec J1H 5N4, Canada
  • University of Sherbrooke
    Sherbrooke, Quebec, Canada
08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jun 2013, a primary completion of Sep 2013 and a completion of Sep 2013. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 10, 2013
First posted
Apr 11, 2014
Start
Jun 2013
Primary completionActual
Sep 2013
CompletionActual
Sep 2013
Last update
Apr 11, 2014
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Apr 11, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02111733
Responsible party
Sponsor
First posted
Apr 11, 2014
Start date
Jun 2013
Primary completion
Sep 2013
Completion
Sep 2013
Last update
Apr 11, 2014

Study contacts

Michel Nguyen, MD
principal investigator · Centre de recherche du Centre hospitalier universitaire de Sherbrooke

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2014. You cannot join it, but the record below documents what was studied.

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