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Status unknownNCT02104453Updated Nov 14, 2014

Comparative Evaluation of Three Airway Maneuvers in the Unconscious Apneic Person

An interventional study of airway maneuver in Airway Morbidity, sponsored by Tri-Service General Hospital. Status unknown at 1 site in Taiwan. Open to participants aged 20 Years to 80 Years. Per ClinicalTrials.gov, last updated 2014-11-14.

Sponsored by Tri-Service General Hospital · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Nov 2014), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
120
Allocation
Randomized
Ages
20 Years to 80 Years
Sex
All
01

Study summary

One-handed E-C clamp mask holding technique, two-handed mask ventilation with jaw thrust, and two-handed mask ventilation with triple airway maneuver are three common airway management maneuvers. Sniffing position may improve ventilation between these three maneuvers. The investigators hypothesize that ventilation efficiency may be different between these three maneuvers whether the patient is in sniffing position or neutral position. The investigators would like to quantify this effect by measuring the expired tidal volume, airway pressure, EtCO2 slope and hemodynamic change between these three maneuvers during anesthesia induction.

Read the detailed description

Mask ventilation is considered a important skill for airway management during general anesthesia induction and for apneic unconscious patients. One-handed E-C clamp mask holding technique, two-handed mask ventilation with jaw thrust, and two-handed mask ventilation with triple airway maneuver are three common airway management maneuvers. However, the efficiency of ventilation between these three maneuvers has to be clarified. Besides, whether sniffing position or neutral position may improve ventilation between these three maneuvers is to be determined. The investigators will collect airway parameters of the patients receiving general anesthesia and measure the expired tidal volume, airway pressure, EtCO2 slope and hemodynamic change between these three maneuvers during anesthesia induction.

02

Conditions studied

  • Airway Morbidity

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Keywords

  • airway maneuver
03

In context

Unconsciousness

89 studies on the registry are indexed under Unconsciousness; 11 are open to participants now.

This study's planned enrollment of 120 is above the median of 51 across 56 interventional studies indexed under Unconsciousness.

Browse Unconsciousness studies →

Lead sponsor

Tri-Service General Hospital is the lead sponsor of 109 studies on the registry; 11 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • adult patients(ASA I-III) scheduled for elective surgery requiring general anesthesia with endotracheal intubation.

Exclusion criteria

Exclusion Criteria:

  • pneumothorax
  • SpO2\<96%(without additional oxygen supply)
  • vocal cord palsy
  • congenital airway abnormality
  • facial trauma or deformity
  • acute upper airway disease
  • inadequate fasting time
  • neck or potential cervical spine disease
  • temporal-mandible joint abnormality
  • head and neck tumor
  • status post radiotherapy
  • pregnancy
  • long term sedative or opioid drug use
  • patient refuse
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Crossover assignment
Masking
Single (Participant)
Enrollment
120 participants (estimated)

Study arms

  • Experimental
    E-C clamp mask holding technique

    the airway maneuver that press the mask against the patient's face (using the "C" of our thumb and forefinger) while pulling the jaw forward (using the "E" of our other fingers behind the mandible), and leaves one hand free to squeeze the bag.

    Procedure: airway maneuver

  • Experimental
    two-handed ventilation with jaw thrust

    the airway maneuver performed with thumbs point toward feet, palms press down and other fingers perform jaw thrust

    Procedure: airway maneuver

  • Experimental
    triple airway maneuver

    the airway maneuver performed with two-handed mask ventilation, jaw thrust and head-tilt chin-lift technique

    Procedure: airway maneuver

Interventions

  • Procedureairway maneuver

    Three-period crossover study: During general anesthesia induction, subjects are assigned to one of the 6 airway maneuver sequences (ABC, CAB, BCA, ACB, CBA, or BAC) in accordance with a randomization schedule. Each maneuver is performed 5 times in a period. Airway maneuver A: E-C clamp mask holding technique; Airway maneuver B: two-handed mask ventilation with jaw thrust airway maneuver; Airway maneuver C: two-handed mask ventilation with triple airway maneuver(combine jaw thrust and head tilt chin lift)

06

What researchers measure

Primary outcomes

  1. Air exchange

    Expired tidal volume, end tidal CO2 slope, peak inspiratory pressure between one-handed E-C clamp mask holding technique, two-handed mask ventilation with jaw thrust, and two-handed mask ventilation with triple airway maneuver

    Time frame: during anesthesia induction

Secondary outcomes

  1. Hemodynamic change

    blood pressure and heart rate variability during ventilation between one-handed E-C clamp mask holding technique, two-handed mask ventilation with jaw thrust, and two-handed mask ventilation with triple airway maneuver

    Time frame: during anesthesia induction

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Study locations

1 of 1 sites recruiting
  • Tri-Service General Hospital
    Taipei, 114, Taiwan
    • Chan, Unervisity · Contact · whcken@gmail.com · 886-2-87923311
    • Chan, Doctorate · Principal investigator
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 14, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02104453
Lead sponsor
Tri-Service General Hospital
Responsible party
Wei-Hung Chan (Anesthesiology Department, Tri-Service General Hospital, Tri-Service General Hospital) — Principal investigator
First posted
Apr 4, 2014
Start date
Jul 2014
Primary completion
Jul 2015 (estimated)
Completion
Jul 2015 (estimated)
Last update
Nov 14, 2014

Study contacts

Chan, doctorate
principal investigator · Tri-Service General Hospital

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Nov 2014. You cannot join it, but the record below documents what was studied.

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