An interventional study of tidal volume and peak airway pressure in Gynecologic Disease, sponsored by Haiyun Wang. Status unknown. Open to female participants aged 18 Years to 65 Years. Per ClinicalTrials.gov, last updated 2014-03-27.
Sponsored by Haiyun Wang · Not applicable and Interventional
The purpose of this study is to compare volume- and pressure- controlled ventilation with laryngeal mask airway Guardian in obese patients undergoing laparoscopic gynecologic surgery in terms of ventilatory efficacy, airway leak pressure (airway protection), ease-of-use and complications.
The Guardian Laryngeal Mask (Ultimate Medical Pty Ltd, Richmond, Vic, Australia) is a new silicone-based single-use extraglottic airway device that forms a seal with the glottis for ventilation and with the hypopharynx for airway protection, and provides a gastric drainage port. The aim of the following perspective, randomized, blind trial study id to compare how the volume-controlled ventilation and pressure-controlled ventilation modes using the Laryngeal Mask Guardian affect the pulmonary mechanics, the gas exchange and the cardiovascular responses particularly in obese patients undergoing gynecological laparoscopy.
154 studies on the registry are indexed under Genital Diseases, Female; 32 are open to participants now.
This study's planned enrollment of 40 is below the median of 80 across 111 interventional studies indexed under Genital Diseases, Female.
Browse Genital Diseases, Female studies →This is the only study on the registry with Haiyun Wang as lead sponsor.
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Exclusion Criteria:
pressure-controlled ventilation: a peak airway pressure that provided a tidal volume of 8-12ml/kg with an upper limit of 35 centimeter water column, respiratory rate 12-16 times per minute.
Procedure: peak airway pressure
volume-controlled ventilation: tidal volume 8-12ml/kg, respiratory rate 12-16 times per minute.
Procedure: tidal volume
In the volume controlled ventilation group using laryngeal mask airway Guardian,a tidal volume of 8-12ml/kg,respiratory rate12-16bpm.
Also known as: TV
In the pressure controlled ventilation group using laryngeal mask airway Guardian,a peak airway pressure that provides a tidal volume of 8-12ml/kg with an upper limit of 35 centimeter water column,respiratory rate12-16bpm.
Also known as: airway peal pressure, peak pressure of aieway
peak pressure
The end-tidal carbon dioxide, the peak pressure, the mean airway pressure, the compliance were continuously monitored during the procedure and they were recorded at T1:just before carbon dioxide insufflation, T2: 30 minutes after carbon dioxide insufflation and T3: 10 minutes after the withdrawal of carbon dioxide. Data on gas exchange (pH、PaCO2、PaO2 ) at T1、T2 and T3 were recorded by artery blood gas analysis.
Time frame: 5 min
Blood pressure
including systolic blood pressure,diastolic blood pressure,mean arterial pressure.
Time frame: intraoperative
heart rate
heart rate
Time frame: intraoperative
Pharyngolaryngeal complication
the presence of either sore throat, dysphonia or dysphagia at 1 and 24 h postoperatively
Time frame: 1,24h
No study locations are listed for this record.
This study is status unknown, as verified in Mar 2014. You cannot join it, but the record below documents what was studied.
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