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CompletedNCT02084186Updated Oct 11, 2016

Moxibustion for Mild and Moderate Ulcerative Colitis

An interventional study of herb-partitioned moxibustion and bran-partitioned moxibustion in Ulcerative Colitis, sponsored by Shanghai Institute of Acupuncture, Moxibustion and Meridian. Completed at 1 site in China. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-10-11.

Sponsored by Shanghai Institute of Acupuncture, Moxibustion and Meridian · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Randomized
Ages
18 Years to 65 Years
Sex
All
01

Study summary

The purpose of this study is to determine whether moxibustion is effective to mild and moderate ulcerative colitis and the effect of moxibustion on metabolism.

02

Conditions studied

  • Ulcerative Colitis
03

In context

Colitis

1,073 studies on the registry are indexed under Colitis; 131 are open to participants now.

This study's enrollment of 60 is close to the median of 60 across 771 interventional studies indexed under Colitis.

Browse Colitis studies →

Lead sponsor

Shanghai Institute of Acupuncture, Moxibustion and Meridian is the lead sponsor of 29 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 65 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Meet the diagnosis of UC
  • Mayo ≤10
  • Patients should have never received any pharmacological therapy or if they are receiving aminosalicylates and/or prednisolone (the dosage has been taken at least 4 weeks, and should be kept the same as before throughout the trial)
  • Patients should have never received antibiotic, biologicals, probiotics, acetaminophen, acetamide and contraceptive.
  • A written informed consent

Exclusion criteria

Exclusion Criteria:

  • Patients with cardiac, encephalic, hepatic, nephric, hematopoietic system, psychotic or any other serious diseases
  • Pregnancy or lactation
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Single (Participant)
Enrollment
60 participants (actual)

Study arms

  • Experimental
    moxibustion group

    herb-partitioned moxibustion on bilateral Tianshu (ST25) and Shangjuxu (ST37)

    Other: herb-partitioned moxibustion

  • Placebo comparator
    bran-partitioned moxibustion

    bran-partitioned moxibustion on bilateral Tianshu (ST25) and Shangjuxu (ST37)

    Other: bran-partitioned moxibustion

Interventions

  • Otherherb-partitioned moxibustion

    Ignited moxa cones are placed upon herbal cake. Herbs are smashed into powder. Every 2.8g medicine powder mix with 3g millet wine and then be pressed into herbal cakes which are 28mm in diameter and 7mm in high with a specific mould. Then the herbal cake with a moxa cone will be fixed on Tianshu and Shangjuxu.

  • Otherbran-partitioned moxibustion

    Ignited moxa cones are placed upon bran cake. Every 2.8g bran powder mix with 3g millet wine and then be pressed into bran cakes which are 28mm in diameter and 7mm in high with a specific mould. Then the bran cake with a moxa cone will be fixed on Tianshu and Shangjuxu.

06

What researchers measure

Primary outcomes

  1. disease activity index (DAI)

    Using Mayo subscore

    Time frame: 3 months

Secondary outcomes

  1. Inflammatory Bowel Disease Questionnaire (IBDQ)

    Time frame: 3 months

  2. symptom score

    Time frame: 3 months

  3. histomorphology observation of intestinal mucosa

    Using the Geboes histology score

    Time frame: 3 months

  4. metabolic profile of intestinal mucosa, urine, plasma and serum

    Time frame: 3 months

07

Study locations

1 site
  • Shanghai Institute of Acupuncture-Moxibustion and Meridian
    Shanghai, 200030, China
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 11, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02084186
Lead sponsor
Shanghai Institute of Acupuncture, Moxibustion and Meridian
Responsible party
Sponsor
First posted
Mar 11, 2014
Start date
Mar 2014
Primary completion
Dec 2015
Completion
Dec 2015
Last update
Oct 11, 2016

Study contacts

Huangan Wu, Doctor
study director · Shanghai Institute of Acupuncture-Moxibustion and Meridian, Shanghai University of Traditional Chinese Medicine

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Dec 2015. You cannot join it, but the record below documents what was studied.

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