An observational study in Head and Neck Cancer, sponsored by University of Aberdeen. Completed at 6 sites in United Kingdom. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-09-08.
Sponsored by University of Aberdeen · Observational
Human papilloma virus (HPV) is a recognised cause of some head and neck cancers. Important questions remain however, regarding the role of specific types of HPV, their effect on prognosis and different subtypes of oral, pharyngeal and laryngeal cancer, interaction with other risk factors (such as smoking and alcohol), and potential geographical differences in the effect of HPV.
Via the Alcohol-Related Cancers and Genetic Susceptibility in Europe (ARCAGE) study, which is an international collaboartive case-control study conducted in 15 centres in 11 European countries, and pooling our results with the HPV-AHEAD consortium, we will conduct a systematic analysis of HPV subtypes known or suspected to be involved in head and neck cancer. This will involve investigation of HPV risk by tumour site (oral, oropharynx, hypopharynx, larynx), tumour stage, country, sex and age, and whether risk is modified by exposure to other known or suspected carcinogens including tobacco, alcohol and medical history.
It is intended that this work will contribute to the development of evidence that may feed into treatment protocols for these cancers as well as evaluations of the feasibility for extending HPV vaccine programs.
2,344 studies on the registry are indexed under Head and Neck Neoplasms; 551 are open to participants now.
This study's enrollment of 141 is above the median of 100 across 441 observational studies indexed under Head and Neck Neoplasms.
Browse Head and Neck Neoplasms studies →University of Aberdeen is the lead sponsor of 170 studies on the registry; 23 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Cases that were previously identified for the HPV-AHEAD case-control study.
Exclusion Criteria:
Cases of Head and Neck Cancer identified in North West England in 2002/2003. Observational study - no intervention other than usual care.
HPV type
Time frame: From surgical/biopsy samples taken in 2002/2003, to be typed in 2014
Vital status
Time frame: 2014
Cancer Reccurrence
Time frame: 2002-2014
Secondary cancers
Time frame: 2002-2014
This study is completed, as verified in Sep 2016. You cannot join it, but the record below documents what was studied.
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University of Aberdeen