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Status unknownNCT02041988Updated Jan 22, 2014

Preemptive Analgesia With Morphine Sulphate in Major Urological Surgery

An observational study in Pain, sponsored by University of Roma La Sapienza. Status unknown at 2 sites in Italy. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2014-01-22.

Sponsored by University of Roma La Sapienza · Observational

The sponsor has not verified this record recently (last verified Jan 2014), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Case-control
Enrollment
40
Ages
18 Years to 75 Years
Sex
All
01

Study summary

In this study safety and efficacy of oral morphine sulphate is evaluated in order to reduce opioids administration during major urological surgery

Read the detailed description

The administration of oral morphine sulfate could be useful to reduce the use of opioids in major urological surgery. This study aims to assess the safety and efficacy of two different oral morphine sulphate doses 0,2 mg/kg vs 0,4mg/kg in major urological surgery.

02

Conditions studied

  • Pain

Keywords

  • premedication
  • oral morphine
  • preemptive analgesia
03

In context

Lead sponsor

University of Roma La Sapienza is the lead sponsor of 388 studies on the registry; 55 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Patients selected for major urological surgery

Inclusion criteria

American Society of Anaesthesiologists physical status classification I/ II, age between 18 - 75, BMI 18 -30

Exclusion criteria

Exclusion Criteria:

American Society of Anaesthesiologists physical status classification III/ IV, renal and hepatic insufficiency, postoperative nausea and vomiting after oral opioids administrations, neurological and psychiatric disorders.

05

Study design

Observational model
Case-control
Enrollment
40 participants (estimated)
Patient registry
No

Groups and cohorts

  • 0,2 mg/kg oral morphine

    Patients have been assigned to two groups of 20 individuals, they have been premedicated with oral morphine sulfate, 0,2 mg/kg group A, 0,4mg/kg group B.During surgery analgesic administration will be monitored

  • 0,4 mg/ kg oral morphine

    morphine and analgesic consumption throughout surgery will be monitored

06

What researchers measure

Primary outcomes

  1. morphine sulphate consumption

    Time frame: six months

Secondary outcomes

  1. vital signs

    Time frame: six months

Other outcomes

  1. VAS score

    Time frame: six months

  2. side effects

    Time frame: six months

07

Study locations

2 of 2 sites recruiting
  • Francesco Cannata
    Rome, 00141, Italy
    Recruiting
  • Policlinico Umberto I
    Rome, 00141, Italy
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 22, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02041988
Lead sponsor
University of Roma La Sapienza
Responsible party
Francesco Cannata (Medical Doctor, University of Roma La Sapienza) — Principal investigator
First posted
Jan 22, 2014
Start date
Feb 2013
Primary completion
Jan 2014
Completion
Jul 2014 (estimated)
Last update
Jan 22, 2014

Study contacts

Francesco FC Cannata, MD
Contact
francesco.cannata@uniroma1.it
+390649970283
Francesco MD Cannata, MD
principal investigator · Policlinico Umberto I

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jan 2014. You cannot join it, but the record below documents what was studied.

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