An interventional study of Group Cognitive Behavioral Therapy and Peer Facilitated Support Group in Hoarding Disorder, sponsored by University of California, San Francisco. Completed at 2 sites in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-02-11.
Sponsored by University of California, San Francisco · Not applicable, Interventional, and Treatment
This study proposes to compare two forms of treatment for Hoarding Disorder (HD), a common and impairing neuropsychiatric syndrome that has a profound impact on the lives and functioning of individuals, families, and society. Specifically, we will compare a novel community-based group treatment led by individuals from the community who are not mental health professionals to the current standard of care treatment for Hoarding Disorder, Cognitive Behavioral Therapy, conducted by psychologists in a group setting. We hypothesized that both treatment types will be similarly effective in reducing hoarding severity.
The study design for this proposal is a stratified, randomized, single-blind, non- inferiority trial comparing the current standard of care for treatment of Hoarding Disorder (HD), Group Cognitive Behavioral Therapy (G-CBT), to an innovative and promising community-based treatment, Group Buried in Treasures (G-BiT). Participants will be stratified by gender, psychiatric status (high vs. low burden of psychiatric symptoms) and insurance status (insured vs. under- or un-insured) so that equal numbers of individuals with each of these characteristics are randomized to each treatment arm. They will then be randomly assigned (randomized) to either G-CBT or G-BiT. Participants will know which treatment group they are assigned to, but those members of the research team who are conducting clinical or neuropsychological assessments or analyzing the data will not; they will be blinded to participant group assignment, and group leaders will be blinded to the psychiatric status, neurocognitive status, insurance status, etc, of participants. The study is a non-inferiority trial, that is, the hypothesis to be tested is that G-BiT is as effective, or no less effective, than G-CBT. We chose a non-inferiority design because we have no reason to believe G-BiT is better than G-CBT and our preliminary data, as well as outcomes previously reported for G- CBT and G-BiT, suggest that these treatments may have similar efficacies.
32 studies on the registry are indexed under Hoarding Disorder; 5 are open to participants now.
This study's enrollment of 323 is above the median of 37 across 28 interventional studies indexed under Hoarding Disorder.
Browse Hoarding Disorder studies →University of California, San Francisco is the lead sponsor of 2,169 studies on the registry; 372 are open to participants now.
Of its 267 completed or terminated interventional studies of FDA-regulated products, 202 (76%) have results posted.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Sixteen sessions of group therapy facilitated by a psychologist.
Behavioral: Group Cognitive Behavioral Therapy
Fifteen sessions of peer-facilitated group support.
Behavioral: Peer Facilitated Support Group
Group therapy over approximately 20 weeks, based on a structured manual adapted from the individual CBT workbook for hoarding by Steketee and Frost (2006). Each session will be 2 hours in length and consists of weekly check-ins, psychoeducation about hoarding, developing understanding and awareness of one's hoarding symptoms and patterns, behavior modification, cognitive restructuring, goal-setting, motivational enhancement, in vivo and imaginal exposure for discarding and acquisition, executive skills training (organization, sorting, planning, decision-making, problem-solving, etc.), guidelines on establishing "clutter buddies", and relapse prevention. Groups will be led by clinical postdoctoral psychology fellows in the Department of Psychiatry at UCSF.
Fifteen sessions of peer facilitated, group support, over the course of 20 weeks, based on a structured manualized approach (Buried in Treasures: Help for Compulsive Acquiring, Saving, and Hoarding). Each session will be 2 hours in length. In this model, two trained peers, usually, but not necessarily, with personal lived experience of hoarding, will guide the group chapter by chapter through the Buried in Treasures manual.
Saving Inventory-Revised (SI-R)
This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. The SI-R is scored on a scale of 0-92. Higher scores indicate more severe hoarding, and scores of 42 and over are considered clinically significant hoarding. Although subscale scores can be calculated, this study uses total scores as the primary outcome.
Time frame: Administered at screening before start of treatment groups and after last treatment group (20 weeks later).
Activities of Daily Living Scale, Hoarding (ADL-H)
The ADL-H is a 15-item self-report questionnaire that measures hoarding specific difficulties or problems that may impact daily functioning. It includes questions on activities affected by clutter or hoarding, problems in the home, and safety issues. For this study, the score on each ADL-H item was summed to create a total score ranging from 0 to 75. Higher scores indicate more severe functional impairment due to hoarding.
Time frame: Administered at baseline and after last treatment group (20 weeks later).
Recruitment occurred during April 2014 through February 2016. Participants were individuals with Hoarding Disorder recruited primarily through the Mental Health Association - San Francisco and flyers in the bay area (e.g. community center boards, coffee shops, laundry mats, libraries).
| Milestone | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group |
|---|---|---|
| Started | 160 | 163 |
| Completed | 118 | 113 |
| Not completed | 42 | 50 |
| Withdrew: Lost to follow-up | 14 | 9 |
| Withdrew: Withdrawal by subject | 28 | 41 |
This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. The SI-R is scored on a scale of 0-92. Higher scores indicate more severe hoarding, and scores of 42 and over are considered clinically significant hoarding. Although subscale scores can be calculated, this study uses total scores as the primary outcome.
| units on a scale | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group |
|---|---|---|
| Baseline | 64.5 ± 11.7 | 66.4 ± 11.6 |
| End of Treatment: 20 weeks later | 45.9 ± 15.0 | 47.8 ± 14.2 |
The ADL-H is a 15-item self-report questionnaire that measures hoarding specific difficulties or problems that may impact daily functioning. It includes questions on activities affected by clutter or hoarding, problems in the home, and safety issues. For this study, the score on each ADL-H item was summed to create a total score ranging from 0 to 75. Higher scores indicate more severe functional impairment due to hoarding.
| units on a scale | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group |
|---|---|---|
| Baseline | 29.9 ± 9.5 | 32.0 ± 11.2 |
| End of Treatment: 20 weeks later | 25.5 ± 10.1 | 26.1 ± 8.7 |
This is a 23-item self-report questionnaire that measures hoarding symptoms and their impact, including problems with acquisition, clutter, and difficulty discarding, as well as distress and impairment/interference. Using the SI-R, we obtained longitudinal follow-up data (defined as a second post-treatment assessment of hoarding symptom severity at least three months following completion of treatment). The total SI-R score was used, which ranges from 0-92, higher scores indicating more severe hoarding.
| units on a scale | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group |
|---|---|---|
| Longitudinal Follow-Up: Saving Inventory-Revised (SI-R) | 48.2 ± 14.9 | 47.9 ± 13.9 |
The ADL-H is a 15-item self-report questionnaire that measures hoarding specific difficulties or problems that may impact daily functioning. It includes questions on activities affected by clutter or hoarding, problems in the home, and safety issues. Using the ADL-H, we obtained longitudinal follow-up data (defined as a second post-treatment assessment of hoarding specific difficulties or problems that may impact daily functioning at least three months following completion of treatment). For this study, a total score using the sum of all of the items was created, ranging from 0 to a total possible of 75. Higher scores indicate more severe impairment due to hoarding.
| units on a scale | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group |
|---|---|---|
| Longitudinal Follow-Up: Activities of Daily Living Scale, Hoarding (ADL-H) | 27.6 ± 11.6 | 27.8 ± 9.7 |
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Group Cognitive-Behavioral Therapy | 0/160 (0%) | 0/160 (0%) | 1/160 (0.6%) |
| Peer Facilitated Support Group | 0/163 (0%) | 0/163 (0%) | 2/163 (1.2%) |
| Event | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group |
|---|---|---|
| Voluntary hospitalization due to "alcohol detox" "possible suicidality"Psychiatric disorders | 1/160 | 0/163 |
| SuicidalityPsychiatric disorders | 0/160 | 1/163 |
| Participant FellSocial circumstances | 0/160 | 1/163 |
| Age, Continuous(years) | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group | Total |
|---|---|---|---|
| Mean | 59.0 ± 10.9 | 58.9 ± 10.6 | 59.0 ± 10.7 |
| Sex: Female, Male(Participants) | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group | Total |
|---|---|---|---|
| Female | 117 | 124 | 241 |
| Male | 43 | 39 | 82 |
| Race/Ethnicity, Customized(Participants) | Group Cognitive-Behavioral Therapy | Peer Facilitated Support Group | Total |
|---|---|---|---|
| Race/Ethnicity Characteristics — American Indian/Alaskan Native | 0 | 1 | 1 |
| Race/Ethnicity Characteristics — Asian | 16 | 17 | 33 |
| Race/Ethnicity Characteristics — Black/African American | 17 | 6 | 23 |
| Race/Ethnicity Characteristics — Hispanic | 9 | 8 | 17 |
| Race/Ethnicity Characteristics — Native Hawaiian/Other Pacific Islander | 2 | 1 | 3 |
| Race/Ethnicity Characteristics — Other or Multiracial | 23 | 23 | 46 |
| Race/Ethnicity Characteristics — White | 89 | 101 | 190 |
| Race/Ethnicity Characteristics — Prefer not to answer | 4 | 5 | 9 |
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2020. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
University of California, San Francisco →