An interventional study of rhythmic auditory stimulation in Parkinson's Disease, sponsored by Chang Gung University. Status unknown at 1 site in Taiwan. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2014-01-16.
Sponsored by Chang Gung University · Not applicable, Interventional, and Treatment
Parkinson's disease (PD) is a progressive degenerative disease of central nervous systems deficit. The clinical symptoms of Parkinson's disease include the following motor tasks: difficult in initiating movement, performing rhythmic movement or serial movement, the ability of learning motor movement is also affected. The primary treatment for Parkinson's disease is medical treatment; surgery is used if in need. Rehabilitation such as physical therapy, which aims to improve patient's quality of life and functions, is a non-invasive treatment and value for PD patients. Auditory cue is a technique that widely applied on training patients with Parkinson's disease, and some researches revealed that auditory cueing could improve motor performance. However, the mechanism under this treatment technique is still unknown.
This study is to investigate the effect of auditory cueing on rhythmic finger movement in patients with Parkinson's disease. To investigate the mechanism under auditory cueing, neurophysiological data such as motor cortex excitability and blood flow in cortical cortex will be obtained by using Transcranial magnetic stimulation (TMS) and near infrared spectroscopy (NIRS).
4,583 studies on the registry are indexed under Parkinson Disease; 1,097 are open to participants now.
This study's planned enrollment of 38 is close to the median of 40 across 3,365 interventional studies indexed under Parkinson Disease.
Browse Parkinson Disease studies →Chang Gung University is the lead sponsor of 66 studies on the registry; 13 are open to participants now.
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Exclusion Criteria:
intervention group which receive auditory cueing while performing movement
Procedure: rhythmic auditory stimulation
control group which performing movement after listen to required movement rhythm.
Participants perform the finger tapping at the same time give rhythmic auditory stimulation ,and need to execute tapping with auditory stimulation.
Finger Tapping
Record pre-test and post-test change.
Time frame: Baseline,45-60 minutes.
Motor evoked potential
Use single-pulse TMS to assess Motor evoked potential change.
Time frame: Baseline,45-60 minute
Intracortical inhibition & Intracortical facilitation
Use paired-pulse TMS to record pre-test and post-test change.
Time frame: Baseline,45-60 minutes
Blood oxygen dependent level
Use Near-infrared spectroscopy to record pre-test, in experiment, and post-test change.
Time frame: Baseline, in experiment,45-60 minutes
The record gives a start of Aug 2013, a primary completion of Aug 2014 and a completion of Aug 2014. It does not say whether these dates are actual or estimated.
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This study is status unknown, as verified in Jan 2014. You cannot join it, but the record below documents what was studied.
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Chang Gung University