An observational study in First Trimester Pregnancy, Fetal Heart Activity Absent and Absence of Fetal Pole on Ultrasonographic Examination., sponsored by Bakirkoy Dr. Sadi Konuk Research and Training Hospital. Status unknown at 1 site in Turkey. Open to female participants. Per ClinicalTrials.gov, last updated 2013-11-20.
Sponsored by Bakirkoy Dr. Sadi Konuk Research and Training Hospital · Observational
The finding that ischemia-modified albumin (IMA) is increased in pre-eclamptic pregnancy suggests a role for IMA as a potential biomarker for abnormal placental development related to miscarriage.This study was undertaken to evaluate IMA levels in women with recurrent pregnancy loss (RPL).
Ischemia-modified albumin (IMA) measured by the albumin cobalt binding test is a relatively new biomarker in the identification of myocardial ischemia. Experimental studies have shown that pregnancies normally develop in a relatively hypoxic intrauterine environment, and the subsequent reperfusion and oxidative stress is important for physiological trophoblast development. The finding that maternal serum IMA levels are raised so early in pregnancy provides further support for IMA as a potential marker for abnormal placental development that may be related to early pregnancy loss. In this study, we aimed to evaluate maternal circulating IMA levels in women with RPL by comparing them with healthy controls.
320 studies on the registry are indexed under Abortion, Spontaneous; 53 are open to participants now.
This study's planned enrollment of 180 is close to the median of 200 across 140 observational studies indexed under Abortion, Spontaneous.
Browse Abortion, Spontaneous studies →Bakirkoy Dr. Sadi Konuk Research and Training Hospital is the lead sponsor of 118 studies on the registry; 14 are open to participants now.
Counted across the registry records on this site, refreshed daily.
first trimester pregnancy with absence of fetal cardiac activity
Exclusion Criteria:
first trimester pregnant women
first trimester pregnancy with absence of fetal cardiac activity or absence of fetal pole on ultrasonographic examination Patients with a history of two or more unexplained first trimester miscarriages and no live births were included in the study.
Time frame: under 14 w gestation
This study is status unknown, as verified in Nov 2013. You cannot join it, but the record below documents what was studied.
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Bakirkoy Dr. Sadi Konuk Research and Training Hospital