An interventional study of Prescription synchronization in Chronic Disease, Cardiovascular Disease and Diabetes Mellitus, sponsored by Brigham and Women's Hospital. Terminated at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-01-11.
Sponsored by Brigham and Women's Hospital · Not applicable, Interventional, and Health services research
The aim of this study is to evaluate if synchronizing when patients with diabetes and/or coronary artery disease fill their prescriptions improves long-term adherence to these medications.
4,904 studies on the registry are indexed under Cardiovascular Diseases; 919 are open to participants now.
This study's enrollment of 3,675 is above the median of 100 across 2,738 interventional studies indexed under Cardiovascular Diseases.
Browse Cardiovascular Diseases studies →Brigham and Women's Hospital is the lead sponsor of 1,236 studies on the registry; 224 are open to participants now.
Of its 116 completed or terminated interventional studies of FDA-regulated products, 64 (55%) have results posted.
Counted across the registry records on this site, refreshed daily.
We will enroll patients 18 years of age and older who within 6 months of study enrollment have filled ≥ 2 medications intended for long-term use (i.e. maintenance medications) by mail order at CVS Caremark. At least 1 of these 2 medications of must be for the treatment of diabetes or cardiovascular disease. In addition, these medications must be delivered on two or more unique delivery dates, there must be at least one refill remaining for all eligible medications and either all or none of their prescriptions must be enrolled in the ReadyFill@Mail program (see Intervention Description for details).
Behavioral: Prescription synchronization
Each patient's medication that has the greatest quantity of pills on hand after randomization will be defined as the "index "medication and partial supplies will be provided for all other eligible medications in order to synchronize all of a patient's medication. Prescribers will be contacted for a new prescription to ensure all eligible medications are on the same renewal schedule. Randomization will occur within strata of whether patients are enrolled in the "ReadyFill@Mail" program. Once synchronized, patients who are not enrolled in the ReadyFill@Mail program will initiate their own refills. Patients who are enrolled in the ReadyFill@Mail program will have their refills automatically filled, however patients may disenroll from ReadyFill@Mail at any time, in which case they will initiate their own refills. Patients may disenroll in whole or in part from the program at any point.
Medication adherence
Average adherence to medications for the treatment of cardiovascular disease and diabetes medications as assessed using administrative pharmacy claims
Time frame: 12 months
Full adherence to medications for the treatment of diabetes or cardiovascular disease
Percent of subjects achieving full adherence (defined as a Medication Possession Ratio \> 80%) to medications for cardiovascular disease and diabetes
Time frame: 12 months
Rates of de-synchronization
Rate at which members whose prescriptions have been synchronized elect to discontinue with the synchronization during the study period
Time frame: 12 months
This study is terminated, as verified in Jan 2016. You cannot join it, but the record below documents what was studied.
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