An interventional study of Pecan-containing diet and Nut-free diet in Cardiovascular Disease Risk and Type 2 Diabetes Risk, sponsored by Tufts University. Completed at 1 site in United States. Open to participants aged 50 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-04-25.
Sponsored by Tufts University · Not applicable, Interventional, and Basic science
The objective of this randomized, controlled feeding study is to investigate the potential health benefits of a pecan-containing diet. The investigators hypothesize the chronic consumption of pecans will improve an array of biomarkers related to cardiovascular disease and type 2 diabetes risk, including indices of oxidative stress, antioxidant activity, inflammation, endothelial function, and insulin resistance when compared with a control diet that is absent nuts.
4,904 studies on the registry are indexed under Cardiovascular Diseases; 920 are open to participants now.
This study's enrollment of 28 is below the median of 100 across 2,738 interventional studies indexed under Cardiovascular Diseases.
Browse Cardiovascular Diseases studies →Tufts University is the lead sponsor of 225 studies on the registry; 24 are open to participants now.
Of its 10 completed or terminated interventional studies of FDA-regulated products, 7 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Test diet containing 1.5 oz pecans/2000 kcal/day for 28 days
Other: Pecan-containing diet
Placebo diet containing no nuts or nut products, and identical in total fat and fiber as the test diet, for 28 days
Other: Nut-free diet
Also known as: Isocaloric diet containing 1.5 oz pecans per 2000 kcal per day for 28 days
Also known as: Isocaloric diet absent nuts and matched for total fat and fiber for 28 days.
Change in biomarkers of oxidative stress compared with control diet
Time frame: Baseline and 4 weeks
Change in biomarkers of inflammation compared with control diet
Time frame: Baseline and 4 weeks.
Change in biomarkers of endothelial function compared with control diet
Time frame: Baseline and 4 weeks.
Change in biomarkers of antioxidant activity compared with control diet
Time frame: Baseline and 4 weeks
Change in biomarkers of insulin resistance compared with control diet
Time frame: Baseline and 4 weeks
Change in blood pressure compared with control diet
Time frame: Baseline and 4 weeks
Change in plasma lipid profile compared with control diet
Time frame: Baseline and 4 weeks.
This study is completed, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.
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Tufts University