A Phase 4 interventional study of Remote ischemic preconditioning at left upper arm and Control group in Patients With Elective Aortic Valve Replacement, sponsored by Yonsei University. Completed at 1 site in South Korea. Open to participants aged 20 Years to 90 Years. Per ClinicalTrials.gov, last updated 2016-11-22.
Sponsored by Yonsei University · Phase 4, Interventional, and Prevention
The aim of this study is to investigate whether RIPC protects the heart against ischemia reperfusion injury on the concentrically hypertrophied myocardium
125 studies on the registry are indexed under Hypertrophy, Left Ventricular; 24 are open to participants now.
This study's enrollment of 79 is below the median of 120 across 73 interventional studies indexed under Hypertrophy, Left Ventricular.
Browse Hypertrophy, Left Ventricular studies →Yonsei University is the lead sponsor of 1,410 studies on the registry; 235 are open to participants now.
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Exclusion Criteria:
Procedure: Remote ischemic preconditioning at left upper arm
Procedure: Control group
Placement of automated cuff-inflator on the left upper arm after induction of anesthesia RIPCgroup-3 cycles of 5 min ischemia (300 mmHg inflation) \& 5 min reperfusion (deflation)
keeping the cuff deflated
Serum levels of CK-MB and Tn-T
Time frame: baseline
Serum levels of CK-MB and Tn-T
Time frame: 12-hour after surgery
Serum levels of CK-MB and Tn-T
Time frame: 24-hour after surgery
Myocardial activation of protective signaling pathway
Time frame: Before commencement of CPB
Myocardial activation of protective signaling pathway
Time frame: After taking off CPB
This study is completed, as verified in Nov 2016. You cannot join it, but the record below documents what was studied.
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Hypertrophy, Left Ventricular →