An interventional study of Magnesium Sulfate and Normal saline in Colorectal Cancer, sponsored by Seoul National University Bundang Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years to 90 Years. Per ClinicalTrials.gov, last updated 2015-11-20.
Sponsored by Seoul National University Bundang Hospital · Not applicable, Interventional, and Prevention
Magnesium sulphate is given to the patients during the colorectal cancer surgery under the hypothesis that it would attenuate the postoperative hypercoagulability. The investigators intend to characterize the changes of coagulation in colorectal cancer patients by using the point-of-care device after the infusion of magnesium sulphate.
5,599 studies on the registry are indexed under Colorectal Neoplasms; 1,459 are open to participants now.
This study's enrollment of 44 is below the median of 77 across 4,123 interventional studies indexed under Colorectal Neoplasms.
Browse Colorectal Neoplasms studies →Seoul National University Bundang Hospital is the lead sponsor of 368 studies on the registry; 55 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Magnesium sulfate infusion during a operation period. Infusion regimen: 1. Bolus 50 mg/kg of magnesium sulfate in 100 ml normal saline over 15 minutes 2. Infusion 15 mg/kg/h of magnesium sulfate throughout the operation
Drug: Magnesium Sulfate
administration of normal saline as a same volume of magnesium sulphate as a same method.
Drug: Normal saline
Change of maximum clot firmness (MCF) of FIBTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Clotting time (CT) of INTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Clot firmness time (CFT) of INTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Alpha angle of INTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of MCF of INTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of CT of EXTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of CFT of EXTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Alpha angle of EXTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of MCF of EXTEM
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Hemoglobin
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Platelet count
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of International normalized ratio of prothrombin time
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Activated partial thrombin time
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
Change of Fibrinogen
Time frame: 1 day before a operation, 1 hour after finishing a operation, and a postopearative 3 day
This study is completed, as verified in Nov 2013. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Seoul National University Bundang Hospital