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WithdrawnNCT01922960Updated Nov 29, 2017

Microcirculatory Assessment in Patients With Trauma and Severe Burns

An interventional study of micro-imaging in Burns and Trauma, sponsored by University of South Alabama. Withdrawn at 1 site in United States. Open to participants aged 19 Years to 80 Years. Per ClinicalTrials.gov, last updated 2017-11-29.

Sponsored by University of South Alabama · Not applicable, Interventional, and Basic science

Why this study was withdrawn
investigators decided not to move forward with project
Phase
Not applicable
Study type
Interventional
Enrollment
0
Allocation
Not applicable
Ages
19 Years to 80 Years
Sex
All
01

Study summary

Predict the development of multiple organ failure in patients with trauma and severe burns.

Read the detailed description

Microvascular alterations are frequently seen in patients with sepsis, trauma, burns and those who are hemodynamically uncompensated(Shock).

The use of the Microscan is a non-invasive approach to visualize and assess impaired mucosal microcirculation in order to identify early on patients who are predisposed for MOF (multiple organ failure)

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Conditions studied

  • Burns
  • Trauma

Keywords

  • trauma
  • multiple organ dysfunction syndrome
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In context

Wounds and Injuries

5,056 studies on the registry are indexed under Wounds and Injuries; 861 are open to participants now.

Browse Wounds and Injuries studies →

Lead sponsor

University of South Alabama is the lead sponsor of 28 studies on the registry; 5 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
19 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients with severe burns/trauma ages 19-80. Patients undergoing elective abdominal or cardiothoracic surgery ages 19-69 years old

Exclusion criteria

Exclusion Criteria:

  • Patients undergoing elective surgery \< 19 years old.
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Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
0 participants (actual)

Study arms

  • Other
    micro-imaging

    Sublingual or subconjunctival micro-imaging of the microcirculation taken for 3 minute intervals at certain timepoints. Timepoints for burn/trauma subjects: Day0, Day1,Day2,Day6 \& Day7 Timepoints for general surgery population: post-induction, prior to resection, after resection,\& closing of surgical wound.

    Other: micro-imaging

Interventions

  • Othermicro-imaging

    micro-imaging

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What researchers measure

Primary outcomes

  1. dysfunctional capillary density correlates with development of multiple organ failure

    Time frame: approximately 1 year to assess outcome measure

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Study locations

1 site
  • University of South Alabama Medical Center
    Mobile, Alabama 36617, United States
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Nov 29, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01922960
Lead sponsor
University of South Alabama
Responsible party
William Richards (Study Chair and Principle Investigator, University of South Alabama) — Principal investigator
First posted
Aug 14, 2013
Start date
Apr 7, 2012 (estimated)
Primary completion
Feb 2014
Completion
Feb 2014
Last update
Nov 29, 2017

Study contacts

William O Richards, MD
study chair · University of South Alabama, Department of Surgery

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.

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