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CompletedNCT01882582Updated May 4, 2016

Evaluation of Immune Signaling Networks in Healthy Human Volunteers

An observational study in Normal Immune Cell Function, sponsored by Martin Angst. Completed at 1 site in United States. Open to participants aged 18 Years to 50 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-05-04.

Sponsored by Martin Angst · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
25
Ages
18 Years to 50 Years
Sex
All
01

Study summary

The purpose of this study is to better understand whether and to what extent the activity of immune cells in blood varies over time under normal conditions as assessed in healthy subjects. Results of this study will provide the foundation for helping us evaluate changes in immune cell activities in response to surgery and drugs used in anesthesia. The overall purpose of our research is to understand immune health in the context of anesthesia and surgery.

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Conditions studied

  • Normal Immune Cell Function
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In context

Lead sponsor

Martin Angst is the lead sponsor of 7 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 50 Years
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Probability sample

Study population

Study population consists of a community sample.

Inclusion criteria

  1. Age 18-50
  2. Good general health

Exclusion criteria

Exclusion Criteria:

  1. Recent cold or flu
  2. Chronic use of medications affecting the immune system
  3. Chronic illness
  4. Smoking habit
  5. History of drug abuse
  6. Current recreational drug use
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
25 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. Numerical and functional changes of circulating immune cells over time in healthy individuals

    This is an exploratory study. Numerical and functional (phosphorylation of signaling molecules and transcription factors) behavior of all circulating immune cells will be captured. Blood specimens collected at referenced time points will be analyzed with mass cytometry.

    Time frame: Day 1, Day 2, Day 7, Day 28

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Study locations

1 site
  • Stanford University
    Stanford, California 94305, United States
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 4, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT01882582
Lead sponsor
Martin Angst
Responsible party
Martin Angst (Professor of Anesthesia, Stanford University) — Sponsor-investigator
First posted
Jun 20, 2013
Start date
Aug 2012
Primary completion
Jul 2013
Completion
Jul 2013
Last update
May 4, 2016

Study contacts

Martin S Angst, MD
principal investigator · Stanford University SOM

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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Discussion

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