An interventional study of Volume expansion in Coronary Artery Occlusive Disease, sponsored by Yonsei University. Completed at 1 site in Korea, Republic of. Open to participants aged 20 Years and older. Per ClinicalTrials.gov, last updated 2013-04-19.
Sponsored by Yonsei University · Not applicable, Interventional, and Diagnostic
The aim of this study is to investigate usefulness of the respirophasic variation in carotid artery peak flow velocity measured by Doppler ultrasound, which is noninvasive and easily accessible, as a predictor of fluid responsiveness in patients with coronary artery disease.
2,839 studies on the registry are indexed under Coronary Disease; 311 are open to participants now.
This study's enrollment of 40 is below the median of 124 across 1,583 interventional studies indexed under Coronary Disease.
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Other: Volume expansion
Also known as: volume expansion with 6 mL/kg of 6% hydroxylethyl starch 130/0.4
Predictive power of the respirophasic carotid flow peak velocity variation for the fluid responsiveness
After induction of anesthesia, peak velocity of carotid artery blood flow is measured by the pulsed wave Doppler signal obtained from the left common carotid artery. Respirophasic variation of the peak velocity is defined as the difference between the maximum and the minimum values of peak velocity divided by the mean of the two values during one respiratory cycle. Fluid responder is defined as a patient whose stroke volume index is increased ≥15% after volume expansion. The receiver operating characteristic curve analysis to descriminiate fluid responder is performed.
Time frame: Measurement of respirophasic carotid flow peak velocity variation before the volume expansion
This study is completed, as verified in Apr 2013. You cannot join it, but the record below documents what was studied.
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Yonsei University