An interventional study of laparoscopic liver resection in Insulin Resistance, sponsored by Sir Run Run Shaw Hospital. Completed at 1 site in China. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2013-03-27.
Sponsored by Sir Run Run Shaw Hospital · Not applicable, Interventional, and Health services research
The purpose of this study is to determine whether the postoperative insulin resistance and cytokine release would be attenuated in laparoscopic compared with open liver resection.
1,960 studies on the registry are indexed under Insulin Resistance; 306 are open to participants now.
This study's enrollment of 52 is above the median of 40 across 1,536 interventional studies indexed under Insulin Resistance.
Browse Insulin Resistance studies →Sir Run Run Shaw Hospital is the lead sponsor of 123 studies on the registry; 64 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
postoperative insulin resistance calculated by serum insulin and blood glucose
At baseline prior to surgery, and 3hr, 12hr, 24hr, 72hrs after operation, blood glucose and insulin was measured. Insulin resistance is assessed by the HOMAIR(homeostatic model assessment of insulin resistance) score which is calculated through the mathematic formula: HOMAIR= FI ×FG/22.5, where FI= fasting serum insulin(μU/mL), FG= fasting plasma glucose (mmol/L), and 22.5 is a constant.
Time frame: within the first 72hrs after operation
cytokine changement including IL-1β, IFN-γ, IL-4 and IL-10 before and after operation
At baseline before operation and 0, 3hr, 12hr, 24hr, D3, D5 after operation, duplicated samples were drawn to analyze serum IL-1β, IFN-γ, IL-4 and IL-10.
Time frame: within 5 days after operation
This study is completed, as verified in Mar 2013. You cannot join it, but the record below documents what was studied.
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Sir Run Run Shaw Hospital