An observational study in Takayasu's Arteritis, Giant Cell Arteritis and Arteritis, sponsored by The Cleveland Clinic. Completed at 1 site in United States. Open to participants aged 18 Years to 100 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-01-27.
Sponsored by The Cleveland Clinic · Observational
The purpose of this study is to evaluate the ability of contrast enhanced carotid ultrasound to serve as an indicator of disease activity in patients with Takayasu's arteritis or Giant Cell arteritis and to determine if patients with active arteritis have a thickening of their blood vessel walls compared to healthy people of the same age and gender.
Takayasu's arteritis and Giant Cell arteritis are chronic, relapsing diseases of the large arteries which can lead to significant narrowing of the arteries through episodes of inflammation within the artery walls. The changes in the vessel walls will be determined by an ultrasound test looking at and measuring: carotid vessel wall changes called carotid Intimal-Media Thickness (cIMT) and the presence of new blood vessels (neovascularization) using a contrast agent. Ultrasound findings will be correlated with markers of inflammation in the blood, findings from other radiology studies (such as MRI) already ordered as part of routine clinical care, and physical exam findings and symptoms of consistent with disease activity. 15 arteritis patients and 5 healthy controls will be recruited.
135 studies on the registry are indexed under Polymyalgia Rheumatica; 28 are open to participants now.
This study's enrollment of 7 is below the median of 114 across 65 observational studies indexed under Polymyalgia Rheumatica.
Browse Polymyalgia Rheumatica studies →The Cleveland Clinic is the lead sponsor of 818 studies on the registry; 118 are open to participants now.
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Patients with Takayasu's arteritis or giant cell arteritis will be screened from the clinics of the Vasculitis Clinic and the Vascular Medicine Clinic at the Cleveland Clinic.
Exclusion Criteria:
Correlation between carotid IMT and neovascularization and disease activity
Time frame: 3 days
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jan 2017. You cannot join it, but the record below documents what was studied.
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