ClinicalTrials.gg
Status unknownNCT01742728Updated Dec 5, 2012

Nagasaki and Tokushima

An observational study in Periodontitis, sponsored by University of Tokushima. Status unknown at 1 site in Japan. Open to participants aged 20 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-12-05.

Sponsored by University of Tokushima · Observational

The sponsor has not verified this record recently (last verified Dec 2012), so the status shown — last known as Recruiting — may be out of date.
Study type
Observational
Model
Cohort
Time perspective
Cross-sectional
Enrollment
2,000
Ages
20 Years and older
Sex
All
01

Study summary

we analyzed the relationship between oxidative stress, immunoglobulin G antibody titers, cytokines, and periodontitis through community-based study held in the Goto city, Japan.

02

Conditions studied

  • Periodontitis

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Keywords

  • oxidative stress, antioxidant, periodontitis, serum immunoglobulin G
  • antibody titer
03

In context

Periodontitis

1,664 studies on the registry are indexed under Periodontitis; 328 are open to participants now.

This study's planned enrollment of 2,000 is above the median of 89 across 441 observational studies indexed under Periodontitis.

Browse Periodontitis studies →

Lead sponsor

University of Tokushima is the lead sponsor of 3 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years and older
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

community sample

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

more than 15 teeth

Exclusion criteria

Exclusion Criteria:

less than 15 teeth

05

Study design

Observational model
Cohort
Time perspective
Cross-sectional
Enrollment
2,000 participants (estimated)

Groups and cohorts

  • Nagasaki

    Sample collection

  • Tokushima

    Oxidative stress, cytokine

  • Kanagawa

    oxidative stress

06

What researchers measure

Primary outcomes

  1. oxidative stress and periodontitis

    reactive oxygen metabolites were measured. immunoglobulin G antibodies were measured by enzyme-linked immunosorbent assay.

    Time frame: participants will be followed by an expected average of 1 year.

07

Study locations

1 of 1 sites recruiting
  • University of Nagasaki
    Nagasaki, Goto, Japan
    • Toshiyuki Saito · Contact · +81-(95)-819-7662
    Recruiting
08

References and documents

Publications

  • Hayashida H, Kawasaki K, Yoshimura A, Kitamura M, Furugen R, Nakazato M, Takamura N, Hara Y, Maeda T, Saito T. Relationship between periodontal status and HbA1c in nondiabetics. J Public Health Dent. 2009 Summer;69(3):204-6. doi: 10.1111/j.1752-7325.2009.00122.x. PubMed 19486462 ↗
  • Tamaki N, Yoshino F, Fukui M, Hayashida H, Yoshida A, Kitamura M, Iwasaki T, Furugen R, Kawasaki K, Nakazato M, Maeda T, Kokeguchi S, Yamamoto T, Lee MC, Ito HO, Saito T. Relationship among salivary antioxidant activity, cytokines, and periodontitis: the Nagasaki Island study. J Clin Periodontol. 2015 Aug;42(8):711-718. doi: 10.1111/jcpe.12438. Epub 2015 Aug 29. PubMed 26227009 ↗

Related links

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 5, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01742728
Lead sponsor
University of Tokushima
Responsible party
Naofumi Tamaki (oxidative stress and periodontitis, University of Tokushima) — Principal investigator
First posted
Dec 5, 2012
Start date
May 2009
Primary completion
Mar 2012
Completion
Mar 2015 (estimated)
Last update
Dec 5, 2012
View the source record on ClinicalTrials.gov ↗

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This study is status unknown, as verified in Dec 2012. You cannot join it, but the record below documents what was studied.

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