A Phase 2 interventional study of Dexamethasone 24 hours and Dexamethasone 12 in Prematurity, sponsored by Assiut University. Completed at 1 site in Egypt. Open to female participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2012-10-02.
Sponsored by Assiut University · Phase 2, Interventional, and Prevention
The investigators sought to determine whether the incidence of neonatal respiratory distress syndrome (RDS) in preterm fetuses is similar with 12- vs 24-hour dosing interval of dexamethasone.
The administration of glucocorticoids to accelerate fetal lung maturity in patients with preterm delivery plays an important role for obstetrics and neonatal care. Many studies have shown that maternal administration of glucocorticoids has a significant beneficial effect in decreasing the incidence of respiratory distress syndrome (RDS) in infants delivered at 28-34 weeks of gestation.
2,554 studies on the registry are indexed under Premature Birth; 498 are open to participants now.
This study's enrollment of 200 is above the median of 84 across 1,689 interventional studies indexed under Premature Birth.
Browse Premature Birth studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
emergent obstetric conditions like:
Those patient will be given 12 hours dexamethasone after randomization
Drug: Dexamethasone 12
Those patient will be give 24 hours dexamethasone after randomization
Drug: Dexamethasone 24 hours
Also known as: glucocorticoids
Also known as: glucocorticoids
respiratory distress syndrome (RDS)
determine whether the incidence of neonatal respiratory distress syndrome (RDS) is similar with 12- vs 24-hour dosing interval of dexamethasone.
Time frame: 6 month
Perinatal mortality
Determine whether the incidence of perinatal mortality is similar with 12- vs 24-hour dosing interval of dexamethasone.
Time frame: 6 month
Neonatal intensive care
Determine whether the incidence of admission to Neonatal intensive care is similar with 12- vs 24-hour dosing interval of dexamethasone.
Time frame: 6 month
This study is completed, as verified in Sep 2012. You cannot join it, but the record below documents what was studied.
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Assiut University