A Phase 4 interventional study of azithromycin and clarithmycin in Peptic Ulcer, Dyspepsia and H-pylori, sponsored by Shahid Sadoughi University of Medical Sciences and Health Services. Completed at 1 site in Iran, Islamic Republic of. Open to participants aged 20 Years to 65 Years. Per ClinicalTrials.gov, last updated 2012-08-17.
Sponsored by Shahid Sadoughi University of Medical Sciences and Health Services · Phase 4, Interventional, and Treatment
The Aim of this study is comparison between two regimens containing clarithromycinand azithromycin.
Eradication of helicobacter pylori is important for treatment of GU but ideal regimen is not available.
HP is resistant to metronidazole and clarithromycin, thus clarithromycin is expensive and it is not available in underdevelopment countries.
There are different articles about replacement clarithromycin with azithromycin as a method of eradication of HP that is decreases length of therapy and increases, effectiveness of drugs and decreases resistance of drugs.
The Aim of this study is comparison between two regimens containing clarithromycinand azithromycin.
146 studies on the registry are indexed under Peptic Ulcer; 25 are open to participants now.
This study's enrollment of 78 is below the median of 165 across 105 interventional studies indexed under Peptic Ulcer.
Browse Peptic Ulcer studies →Shahid Sadoughi University of Medical Sciences and Health Services is the lead sponsor of 4 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Biopsy and archival tissue
A biopsy takes a small piece of tissue to examine. “Archival tissue” is a sample already taken, for example at diagnosis, and kept by the hospital.
Whether a stored sample will do depends on when it was taken, how much there is and what the study needs. Ask whether the study accepts your stored sample or needs a new biopsy.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Azithromycin (Zithromax, Azithrocin ) is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world's best-selling antibiotics. It is derived from erythromycin, with a methyl-substituted nitrogen atom incorporated into the lactone ring, thus making the lactone ring 15-membered.
Drug: azithromycin
Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydophila pneumoniae), skin and skin structure infections. In addition, it is sometimes used to treat legionellosis, Helicobacter pylori, and lyme disease.
Drug: clarithmycin
Azithromycin (Zithromax, Azithrocin ) is an azalide, a subclass of macrolide antibiotics. Azithromycin is one of the world's best-selling antibiotics.\[1\] It is derived from erythromycin, with a methyl-substituted nitrogen atom incorporated into the lactone ring, thus making the lactone ring 15-membered.
Also known as: (Zithromax, Azithrocin
Clarithromycin is a macrolide antibiotic used to treat pharyngitis, tonsillitis, acute maxillary sinusitis, acute bacterial exacerbation of chronic bronchitis, pneumonia (especially atypical pneumonias associated with Chlamydophila pneumoniae), skin and skin structure infections. In addition, it is sometimes used to treat legionellosis, Helicobacter pylori, and lyme disease.
Also known as: Crixan, Claritt, Clarac, Biaxin, Klaricid, Klacid...
H-pylori cinfirmation
confirmation is by endoscopy and biopsy
Time frame: 1-3 months before study
h-pylori eradication confirmation
confirmation of eradication was by endoscopy and biopsy
Time frame: two months after completion of 14 days standard treatment
side effect of study srugs
it was assessed by researcher and self report of patients. variables like nausea, vomiting and diarrhea. the prevalence of each treatment related complain was registered by taking history from patients.
Time frame: during 14 days standard treatment
This study is completed, as verified in Aug 2012. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Studies of the drug tested here: Azithromycin
Shahid Sadoughi University of Medical Sciences and Health Services