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TerminatedNCT01645774Updated Jul 20, 2012

Comparing Pain and Bruising of Subcutaneous Heparin Injection

A Phase 2/3 interventional study of 10s injections duration and 10s injection duration and waiting 10s before withdrawing the needle in Pain and Bruising, sponsored by Mashhad University of Medical Sciences. Terminated. Open to participants aged 53 Years to 69 Years. Per ClinicalTrials.gov, last updated 2012-07-20.

Sponsored by Mashhad University of Medical Sciences · Phase 2/3, Interventional, and Prevention

Phase
Phase 2/3
Study type
Interventional
Enrollment
90
Allocation
Randomized
Ages
53 Years to 69 Years
Sex
All
01

Study summary

Subcutaneous heparin injection is one of the most frequent nurses' clinical care. This study aimed to Identify and compare the effects of four different injection duration on pain and bruising associated with subcutaneous injection of heparin in 90 patients. Four injection methods were used for them:

A: 10s injections duration

B: 10s injection duration and waiting 10s before withdrawing the needle

C: 15s injection duration and waiting 5s before withdrawing the needle

D: 5s injection duration and waiting 15s before withdrawing the needle.

Bruising was measured by a flexible millimeter ruler 48h after each injection; and pain was measured by pain visual analogue scale immediately after the injection. Data will be analyzed by SPSS.

02

Conditions studied

  • Pain
  • Bruising

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Keywords

  • subcutaneous injection heparin
  • injection duration
  • bruising pain
  • decrease pain
  • decrease bruising
03

In context

Pain

10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.

This study's enrollment of 90 is above the median of 66 across 8,493 interventional studies indexed under Pain.

Browse Pain studies →

Lead sponsor

Mashhad University of Medical Sciences is the lead sponsor of 92 studies on the registry; 3 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
53 Years to 69 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Inclination to participate in the study; filling out the form of conscious satisfaction
  • Ability to answer the questions and determining the rate of pain
  • Not being affected by blood clotting difficulties, tissue damages, injuries, and bruises in the site of injection.

Exclusion criteria

Exclusion Criteria:

  • Death,
  • Discharge
05

Study design

Phase
Phase 2 / Phase 3
Primary purpose
Prevention
Allocation
Randomized
Intervention model
Single group
Masking
Double (Participant, Care provider)
Enrollment
90 participants (actual)

Study arms

  • Experimental
    10s injections duration

    10s injections duration

    Procedure: 10s injections duration

  • Experimental
    10s injection duration , waiting 10s

    10s injection duration and waiting 10s before withdrawing the needle

    Procedure: 10s injection duration and waiting 10s before withdrawing the needle

  • Experimental
    15s injection duration,waiting 5s

    15s injection duration and waiting 5s before withdrawing the needle

    Procedure: 15s injection duration and waiting 5s before withdrawing the needle

  • Experimental
    5s injection duration , waiting 15s

    5s injection duration and waiting 15s before withdrawing the needle

    Procedure: 5s injection duration and waiting 15s before withdrawing the needle

Interventions

  • Procedure10s injections duration

    10s injections duration

  • Procedure10s injection duration and waiting 10s before withdrawing the needle

    10s injection duration and waiting 10s before withdrawing the needle

  • Procedure15s injection duration and waiting 5s before withdrawing the needle

    15s injection duration and waiting 5s before withdrawing the needle

  • Procedure5s injection duration and waiting 15s before withdrawing the needle

    5s injection duration and waiting 15s before withdrawing the needle

06

What researchers measure

Primary outcomes

  1. decrease pain

    pain was measured by pain visual analogue scale immediately after the injection.

    Time frame: up to 6 months

  2. bruising

    Bruising was measured by a flexible millimeter ruler 48h after each injection

    Time frame: up to 6 months

07

Study locations

No study locations are listed for this record.

08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jan 2011, a primary completion of Jun 2012 and a completion of Jun 2012. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
May 19, 2012
First posted
Jul 20, 2012
Start
Jan 2011
Primary completionActual
Jun 2012
CompletionActual
Jun 2012
Last update
Jul 20, 2012
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Jul 20, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01645774
Lead sponsor
Mashhad University of Medical Sciences
Responsible party
Tayebe Pourghaznein (faculty member,MSc of Nursing, Mashhad University of Medical Sciences) — Principal investigator
First posted
Jul 20, 2012
Start date
Jan 2011
Primary completion
Jun 2012
Completion
Jun 2012
Last update
Jul 20, 2012

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

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This study is terminated, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.

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