An interventional study of Executive function training in Posttraumatic Stress Disorders, sponsored by University of Missouri, Kansas City. Status unknown at 1 site in United States. Open to male participants aged 18 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2014-12-08.
Sponsored by University of Missouri, Kansas City · Not applicable, Interventional, and Treatment
The purpose of this pilot study is to determine the effects of computer-based training in executive functioning compared to word games on cognitive and emotional aspects of combat-related PTSD.
Many posttraumatic stress disorder (PTSD) patients either choose not to complete or do not achieve optimal response to current first-line behavioral and pharmacologic treatments. Neurocognitive research points to the potential of novel treatments targeting dorsal prefrontal function and inhibition, attention, and working memory processes. This study investigates effects of computer-based training in executive functions compared to word games on cognitive and emotional aspects of combat-related PTSD. Paper-and-pencil questionnaires, interviews, computer-administered testing, and magnetic resonance imaging will be complete before and after the intervention. Results from this pilot study will provide information concerning feasibility and treatment potential of cognitive training for PTSD.
2,284 studies on the registry are indexed under Stress Disorders, Post-Traumatic; 557 are open to participants now.
This study's planned enrollment of 40 is below the median of 70 across 1,897 interventional studies indexed under Stress Disorders, Post-Traumatic.
Browse Stress Disorders, Post-Traumatic studies →University of Missouri, Kansas City is the lead sponsor of 48 studies on the registry; 9 are open to participants now.
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Exclusion Criteria:
Executive function training
Behavioral: Executive function training
Computer-based training in tasks related to verbal processing.
Computer-based training in executive functions, administered via www.lumosity.com website.
Neural activity in prefrontal regions during cognitive and emotional processing measured by functional magnetic resonance imaging.
Time frame: change from baseline to after 6 weeks of training
Cognitive functioning as measured by neuropsychological assessment.
Time frame: change from baseline to after 6 weeks of training
Clinical PTSD symptoms as measured by the Clinician Administered PTSD Scale (CAPS).
Time frame: change from baseline to after 6 weeks of training
This study is status unknown, as verified in Dec 2014. You cannot join it, but the record below documents what was studied.
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Stress Disorders, Post-Traumatic →
University of Missouri, Kansas City