CClinicalTrials.gg
CompletedNCT01628653U-SMARTUpdated Jun 27, 2012

Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training

A Phase 1 interventional study of U-SMART in Mild Cognitive Impairment, sponsored by Seoul National University Bundang Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged 55 Years to 90 Years. Per ClinicalTrials.gov, last updated 2012-06-27.

Sponsored by Seoul National University Bundang Hospital · Phase 1, Interventional, and Treatment

Phase
Phase 1
Study type
Interventional
Enrollment
10
Allocation
Not applicable
Ages
55 Years to 90 Years
Sex
All
01

Study summary

The purpose of this study is to examine feasibility and efficacy of the Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (U-SMART) in the elderly individuals with mild cognitive impairment (MCI).

Read the detailed description

The Spaced Retrieval-based Memory Advancement and Rehabilitation Training (SMART) which consisted of 24 one-hour face-to-face sessions (Lee, Park et al. 2009) was developed based on the spaced retrieval training (SRT), which was effective in improving memory retention span of very mild to mild Alzheimer's disease patients. The Ubiquitous SMART (U-SMART) by transforming the current SMART to a self-administered program using an application working on IPAD was developed, and was examined its feasibility and efficacy in the elderly individuals with mild cognitive impairment.

02

Conditions studied

  • Mild Cognitive Impairment

Keywords

  • Mild cognitive impairment
  • Cognitive rehabilitation
  • Cognitive therapy
  • Spaced retrieval Training
  • Alzheimer's disease
  • Memory enhancement
  • U-healthcare
03

In context

Cognitive Dysfunction

3,842 studies on the registry are indexed under Cognitive Dysfunction; 1,099 are open to participants now.

This study's enrollment of 10 is below the median of 65 across 2,807 interventional studies indexed under Cognitive Dysfunction.

Browse Cognitive Dysfunction studies →

Lead sponsor

Seoul National University Bundang Hospital is the lead sponsor of 368 studies on the registry; 55 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
55 Years to 90 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Aged 55-90
  • Educational level above 1 year and confirmed literacy
  • Diagnosed to mild cognitive impairment by International Working Group on Mild Cognitive Impairment
  • Clinical Dementia Rating (CDR) of 0 or 0.5

Exclusion criteria

Exclusion Criteria:

  • Diagnosed to dementia by DSM-IV
  • Evidence of delirium, confusion
  • Any neurological conditions causing cognitive decline such as Parkinson's disease, brain hemorrhage, brain tumor, normal pressure hydrocephalus
  • Evidence of severe cerebrovascular pathology
  • History of loss-of-consciousness over 1 hour due to head trauma or repetitive head trauma of mild severity
  • History of substance abuse or dependence such as alcohol
  • Presence of depressive symptoms that could influence cognitive function
  • Presence of medical comorbidities that could result in cognitive decline
  • Use of medication that could influence cognitive function seriously
05

Study design

Phase
Phase 1
Primary purpose
Treatment
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
10 participants (actual)

Study arms

  • Experimental
    U-SMART

    U-SMART (Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training)

    Device: U-SMART

Interventions

  • DeviceU-SMART

    4-weeks' training

06

What researchers measure

Primary outcomes

  1. the five-point Likert scales for satisfaction and compliance

    To evaluate the feasibility of the U-SMART, the five-point Likert scales for satisfaction and compliance were applied to all participants.

    Time frame: after 4-weeks treatment

  2. Word List Memory Test of the CERAD Neuropsychological Assessment Battery

    To evaluate the efficacy of the U-SMART, the Word List Memory Test (WLMT) of the CERAD neuropsychological assessment battery was applied to all participants.

    Time frame: after 4-weeks treatment

Secondary outcomes

  1. Mini-Mental State Examination (MMSE)

    Time frame: after 4-weeks treatment

07

Study locations

1 site
  • Seoul National University Bundang Hospital
    Seongnam, Gyeonggi 463-707, Korea, Republic of
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 27, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01628653
Lead sponsor
Seoul National University Bundang Hospital
Collaborators
KT Corporation
Responsible party
Ki Woong Kim (Professor, department of neuropsychiatry, Seoul National University Bundang Hospital) — Principal investigator
First posted
Jun 27, 2012
Start date
Jun 2011
Primary completion
Feb 2012
Completion
Feb 2012
Last update
Jun 27, 2012

Study contacts

Ki Woong Kim, M.D., Ph.D.
principal investigator · Seoul National University Bundang Hospital, Seong-nam, Korea

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion