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Status unknownNCT01612390Updated Jun 5, 2012

Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor

An observational study in Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol, sponsored by Rasha Mohammed Mohammed Badawi. Status unknown at 1 site in Egypt. Open to female participants aged 18 Years to 40 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2012-06-05.

Sponsored by Rasha Mohammed Mohammed Badawi · Observational

The sponsor has not verified this record recently (last verified Jun 2012), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
180
Ages
18 Years to 40 Years
Sex
Female
01

Study summary

Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor

Read the detailed description

Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor as The data from a pharmacokinetics study suggested that the bioavaiblitiy of misoprostol after sub-lingual administration was higher than those after oral or vaginal administration

02

Conditions studied

  • Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol

Keywords

  • postpartum hemorrhage
03

In context

Postpartum Hemorrhage

445 studies on the registry are indexed under Postpartum Hemorrhage; 75 are open to participants now.

This study's planned enrollment of 180 is above the median of 150 across 91 observational studies indexed under Postpartum Hemorrhage.

Browse Postpartum Hemorrhage studies →

Lead sponsor

This is the only study on the registry with Rasha Mohammed Mohammed Badawi as lead sponsor.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

The study will include (180)randomly allocated

Inclusion criteria

  • Women with aheathy singleton pregnancy in spontaneous or induced labor at term .

Exclusion criteria

Exclusion Criteria:

  • Hypersensitivity/Contraindication to prostaglandins Antepartum hemorrhage Multiple pregnancy Cardiac disease Malpresentation Rhesus- negative mother hypersensitive disorders Severe anaemia(hemoglobin\<7g/dl)
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
180 participants (estimated)

Groups and cohorts

  • group 1

    receive 400 Mg sublingual misoprostol.

  • group 2

    receive 600 Mg sublingual misoprostol.

  • group 3

    receive 5IU of intravenous oxytocin.

06

What researchers measure

Primary outcomes

  1. reduce blood loss during third and fourth stages of labor.

    reduce blood loss during third and fourth stages of labor by using misopristol is better than using oxytocin

    Time frame: 1 year

Secondary outcomes

  1. the duration of the third stage of labor ,need for oxytocics ,blood transfusion and any adverse effects of the drugs

    the duration of the third stage of labor ,needed for oxytocics ,blood transfusion and any adverse effects of the drug will be reduced with mesopristol

    Time frame: 1 year

07

Study locations

1 site
  • AinShamsU
    Cairo, 44511, Egypt
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jun 5, 2012, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT01612390
Lead sponsor
Rasha Mohammed Mohammed Badawi
Collaborators
Ain Shams University
Responsible party
Rasha Mohammed Mohammed Badawi (RBadawi, Ain Shams University) — Sponsor-investigator
First posted
Jun 5, 2012
Start date
Aug 2012
Primary completion
Aug 2013 (estimated)
Completion
Dec 2013 (estimated)
Last update
Jun 5, 2012

Study contacts

Rasha mohamed, M.B;B.CH
Contact
abosalma_82@yahoo.com
RBadawi mohamed, M.B;B.CH
principal investigator · Ain Shams University

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2012. You cannot join it, but the record below documents what was studied.

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