An interventional study of Aerobic Exercise Training and Physical Activity Recommendations in Aortic Valve Stenosis, sponsored by Linkoeping University. Terminated at 1 site in Sweden. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-10-17.
Sponsored by Linkoeping University · Not applicable, Interventional, and Treatment
SURVEY OF THE FIELD Aortic stenosis (AS) is the most common valve disease and increasing due to a growing elderly population. The therapy is aortic valve replacement (AVR). Studies on postoperative rehabilitation of AS pts are scarce. In the few studies available, a mix of valve diseases is presented without considering the differences in pathophysiology and the training regimes are not clearly described.
PURPOSE, AIMS \& HYPOTHESIS The investigators purpose is to evaluate whether a supervised cardiac rehabilitation program improves the objective physical capacity and quality of life (QoL) of patients after AVR due to AS, and compare this to patients training by their own. The investigators hypothesize that supervised exercise training may be a more efficient way of rehabilitating these patients.
DESIGN This is a controlled randomized clinical trial comparing 12 weeks of supervised exercise training 3 times per week to home-based training based upon public health recommendations of minimum level of physical activity.
SIGNIFICANCE \& IMPLEMENTATION Positive results would support that an organized program of exercise training improves physical capacity and QoL in AS patients following AVR with potential benefit for both patients and society.
985 studies on the registry are indexed under Aortic Valve Stenosis; 283 are open to participants now.
This study's enrollment of 12 is below the median of 120 across 525 interventional studies indexed under Aortic Valve Stenosis.
Browse Aortic Valve Stenosis studies →Linkoeping University is the lead sponsor of 189 studies on the registry; 40 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
12 weeks of 40 min aerobic bicycle ergometer exercise 3 times per week.
Other: Aerobic Exercise Training
Written and verbal information on minimal level of physical activity recommended.
Other: Physical Activity Recommendations
12 weeks of endurance training, 40 minutes, 3 times per week on ergometer bicycle.
Also known as: Physiotherapy, Physical activity
Written and verbal information on minimal level of physical activity recommended.
Also known as: Exercise
Change in peak oxygen uptake
Physical capacity measured with cardiopulmonary exercise testing (CPET) on bicycle ergometer.
Time frame: Before (within one week before intervention), 1 week after and 12 months after intervention
Change in Health-related Quality of Life
Short-form 36, version 2
Time frame: Before (within one week before intervention), 1 week after and 12 months after intervention
Change in Physical activity level
PAL - Physical activity level, measured with International Physical Activity Questionnary (IPAQ)
Time frame: Before (within one week before intervention), 1 week after and 12 months after intervention
Change in hs-CRP
Time frame: Before (within one week before intervention), 1 week after and 12 months after intervention
Change in NT-pro-BNP
Time frame: Before (within one week before intervention), 1 week after and 12 months after intervention
This study is terminated, as verified in Oct 2017. You cannot join it, but the record below documents what was studied.
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Linkoeping University