An interventional study of Multidisciplinary weaning-ventilator protocol in Weaning Failure and Complication of Respirator [Ventilator], sponsored by Federal University of Uberlandia. Completed at 1 site in Brazil. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2013-03-04.
Sponsored by Federal University of Uberlandia · Not applicable and Interventional
Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers.
The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol to assess whether a systematic approach compared with the physician's judgment only decreases time spent on the ventilator, complications of mechanical ventilation and length of stay in critical care unit.
Federal University of Uberlandia is the lead sponsor of 59 studies on the registry; 3 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Discontinuation of ventilation was based in multidisciplinary protocol.
Other: Multidisciplinary weaning-ventilator protocol
Discontinuation of ventilation was left entirely to the discretion of the physicians.
We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation.
Also known as: Weaning-ventilator protocol
Mortality
Time frame: length of ICU stay (days)
Duration of Weaning From Mechanical Ventilation
Time frame: days
Duration of Mechanical Ventilation
Time frame: days
Length of Intensive Care Unit Stay
Time frame: days
Adult patients hospitalized in the intensive care unit, remained on mechanical ventilation for more than 24 hours and subjected to weaning from mechanical ventilation.
| Milestone | Protocol-directed | Usual Care |
|---|---|---|
| Started | 0 | 269 |
| Completed | 0 | 96 |
| Not completed | 0 | 173 |
| Withdrew: Protocol violation | 0 | 172 |
| Withdrew: Lost to follow-up | 0 | 1 |
| Milestone | Protocol-directed | Usual Care |
|---|---|---|
| Started | 414 | 0 |
| Completed | 139 | 0 |
| Not completed | 275 | 0 |
| Withdrew: Protocol violation | 275 | 0 |
| participants | Protocol-directed | Usual Care |
|---|---|---|
| Mortality | 10 | 14 |
| days | Protocol-directed | Usual Care |
|---|---|---|
| Duration of Weaning From Mechanical Ventilation | 3.6 ± 5.49 | 6.8 ± 9.45 |
Results for this outcome have not been posted.
Results for this outcome have not been posted.
Non-serious events are listed at a 0% frequency threshold.
| Group | Deaths | Serious | Other |
|---|---|---|---|
| Protocol-directed | — | — | — |
| Usual Care | — | — | — |
| Age Continuous(years) | Protocol-directed | Usual Care | Total |
|---|---|---|---|
| Mean | 49.9 ± 20.18 | 43.5 ± 17.89 | 47.28 ± 19.50 |
| Sex: Female, Male(Participants) | Protocol-directed | Usual Care | Total |
|---|---|---|---|
| Female | 38 | 33 | 71 |
| Male | 101 | 63 | 164 |
| Region of Enrollment(participants) | Protocol-directed | Usual Care | Total |
|---|---|---|---|
| Brazil | 139 | 96 | 235 |
This study is completed, as verified in Jan 2013. You cannot join it, but the record below documents what was studied.
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Federal University of Uberlandia