CClinicalTrials.gg
CompletedNCT01454375Updated Oct 3, 2014

Emergency Department Smoking Cessation Study

An interventional study of Referral to QuitNow Services in Tobacco Use Cessation, sponsored by University of British Columbia. Completed at 1 site in Canada. Open to participants aged 19 Years and older. Per ClinicalTrials.gov, last updated 2014-10-03.

Sponsored by University of British Columbia · Not applicable, Interventional, and Health services research

Phase
Not applicable
Study type
Interventional
Enrollment
1,301
Allocation
Randomized
Ages
19 Years and older
Sex
All
01

Study summary

Tobacco smoke claims approximately 6000 lives annually in BC. In this study, the investigators will determine whether referring smoking patients from the Vancouver General Hospital Emergency Department to the investigators provincial QuitNow smoking cessation service will lead to improved patient outcomes, including number of cigarettes smoked, any quit attempts, and actual smoking cessation.

Participants in the usual care arm will receive standard care. Participants in the intervention arm will be eligible for referral to QuitNow Services, where telephone counseling will be offered. Further follow-up on all enrolled patients will be conducted at 1, 3, 6, and 12 months to re-assess smoking status.

The investigators hypothesis is that the intervention arm will have a higher quit rate that the control arm.

Read the detailed description

As the leading cause of preventable deaths in British Columbia (BC), tobacco smoke claims approximately 6000 lives annually in BC. Although 16% of British Columbians smoke, the prevalence of smoking may be as high as 48% in the Emergency Department (ED) patient population. In this study, the investigators will determine whether referring stable adult smoking patients from the Vancouver General Hospital ED directly to the investigators provincial QuitNow smoking cessation service will lead to improved patient outcomes, including number of cigarettes smoked, any quit attempts, and actual smoking cessation. This will be the first ever randomized controlled trial to determine whether smokers referred from the ED to a web and phone based community resource will receive benefit.

Currently, EDs in British Columbia, including VGH, are not routinely counseling patients to stop smoking. However, up to 44% of ED patients do not have a family practitioner and rely solely on EDs for their health care. Therefore, the ED serves as a critical venue where smoking cessation can be initiated or reinforced. The BC Ministry of Health has recently funded a program called QuitNow, which in collaboration with the BC Lung Association, offers smoking cessation advice through an internet resource and a 24-hour telephone quit line. This year, a meta-analysis of randomized controlled trials showed that web-based and computer-based smoking cessation programs led to a significant increase in patients who stopped smoking, with effects that were sustained at 12 months. However, these studies did not include ED patients.

In this trial, participants assigned to the usual care arm will receive standard care, with no additional study-related smoking cessation counseling. Participants assigned to the intervention arm will be eligible for referral to the QuitNow service. In the intervention arm, individuals will receive telephone follow-up from QuitNow at their earliest convenience. For all participants, data will be collected on demographic information, chief complaint, past medical history, smoking history, medications including nicotine replacement therapies, and final diagnosis. The smoking history will include the patient's number of daily cigarettes smoked, years of smoking, any previous quit attempts, and desire to quit. Further telephone follow-up on all enrolled patients will be conducted at 1, 3, 6, and 12 months to re-assess smoking status. We will also determine whether participants were enrolled in or completed the QuitNow Services program. For our initial pilot study, we made 5 calls to each participant at each follow-up period. For this full randomized controlled trial, participants will be called a maximum of 15 times at 12 months.

Data analysis will be performed using individual growth curve analyses with a multi-level regression model. P values of \<0.05 will be considered statistically significant. An intention-to-treat analysis will be performed. If results are found to be significant, a Benjamini-Hochberg adjustment for multiple comparisons will be done. The expected time commitment for each patient will be 15 minutes in the ED and 20 minutes total for 4 follow-up telephone phone calls.

02

Conditions studied

  • Tobacco Use Cessation

Browse trials for

Keywords

  • Smoking
03

In context

Emergencies

1,692 studies on the registry are indexed under Emergencies; 332 are open to participants now.

This study's enrollment of 1,301 is above the median of 145 across 930 interventional studies indexed under Emergencies.

Browse Emergencies studies →

Lead sponsor

University of British Columbia is the lead sponsor of 1,309 studies on the registry; 253 are open to participants now.

Of its 6 completed or terminated interventional studies of FDA-regulated products, 1 (17%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • 19 years of age or older
  • stable (vital signs within normal limits not requiring immediate physician intervention)
  • used a tobacco product in the last 30 days
  • presenting to the Vancouver General Hospital Emergency Department
  • can provide informed consent in English

Exclusion criteria

Exclusion Criteria:

  • cannot provide informed consent
  • sexual assault patients
  • not a resident of British Columbia
  • unable to provide telephone number of email address for follow-up
05

Study design

Phase
Not applicable
Primary purpose
Health services research
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Investigator, Outcomes assessor)
Enrollment
1,301 participants (actual)

Study arms

  • No intervention
    Control Arm

    No change in current practice

  • Experimental
    Referral fo QuitNow Services

    Behavioural - referral to QuitNow Services, smoking cessation counseling telephone line supported by the Ministry of Healthy Living and Sport

    Behavioral: Referral to QuitNow Services

Interventions

  • BehavioralReferral to QuitNow Services

    QuitNow Services is a telephone counseling program supported by the Ministry of Health Living and Sport that counsels individuals to stop smoking

06

What researchers measure

Primary outcomes

  1. Smoking cessation rates between intervention and control arms

    Smoking cessation rate between intervention and control arms at 12 months

    Time frame: 12 months

Secondary outcomes

  1. Smoking cessation rates between intervention and control arms

    Time frame: 1 month

  2. Smoking cessation rates between intervention and control arms

    Time frame: 3 months

  3. Smoking cessation rates between intervention and control arms

    Time frame: 6 months

  4. No of cigarettes smoked daily between intervention and control arms

    Time frame: 1, 3, 6, and 12 months

  5. Differences in readiness for change between the intervention and control arms

    Time frame: 1, 3, 6, and 12 months

  6. Differences in knowledge and attitudes concerning smoking between the intervention and control arms

    Time frame: 1, 3, 6, and 12 months

  7. Differences in use of nicotine replacement therapies between the intervention and control arms

    Time frame: 1, 3, 6, and 12 months

  8. Differences in number of quit attempts between the intervention and control arms

    Time frame: 1,3,6,12 months

07

Study locations

1 site
  • Vancouver General Hospital Emergency Department, University of British Columbia
    Vancouver, British Columbia V5Z 1M9, Canada
08

References and documents

Publications

  • Tsai APY, Tsai JP, Stewart L, Brubacher J, Cheung KW. Prevalence of potential smoking-related conditions among tobacco users in the emergency department and their perception that their visit may be smoking-related. CJEM. 2017 May;19(3):207-212. doi: 10.1017/cem.2016.381. Epub 2016 Oct 17. Erratum In: CJEM. 2017 May;19(3):246. doi: 10.1017/cem.2017.368. PubMed 27748218 ↗
09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Oct 3, 2014, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT01454375
Lead sponsor
University of British Columbia
Collaborators
Vancouver Coastal Health Research Institute
Responsible party
Sponsor
First posted
Oct 19, 2011
Start date
Nov 2011
Primary completion
Feb 2013
Completion
Feb 2013
Last update
Oct 3, 2014

Study contacts

Ka Wai Cheung, MD, MPH
principal investigator · University of British Columbia

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2014. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion