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CompletedNCT01436669Updated Mar 18, 2021

Study of Home Full Blood Count (FBC) Telemonitoring Device for Chemotherapy Patient

An interventional study of Home Telemonitoring System (The Zodiac, Philips Health care) in Cancer, sponsored by Philips Healthcare. Completed at 1 site in United Kingdom. Open to participants aged 19 Years to 75 Years. Per ClinicalTrials.gov, last updated 2021-03-18.

Sponsored by Philips Healthcare · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Not applicable
Ages
19 Years to 75 Years
Sex
All
01

Study summary

The Zodiac, a Philips healthcare telemonitoring system has been devised to allow cancer patients receiving chemotherapy to test their blood count at home. It is anticipated that the system will allow patients and clinicians to reduce the toxic effects of chemotherapy by early diagnosis of neutropenia, anaemia and any associated complications of chemotherapy. It is also anticipated that the system will also allow clinicians to better manage the scheduling of chemotherapy regimes.

Read the detailed description

Philips Healthcare has devised a new home full blood count (FBC) home telemonitoring system which will allow cancer patients receiving chemotherapy to test their blood count at home (haemoglobin, haematocrit, white cell count and neutrophil count). The system will also allow patients to record their temperature and symptoms. The Philips home telemonitoring system is called the Zodiac and consists of a telecommunications hub connected to a haematology analyser. The Hub connects to medical device software running on a remote server which controls the flow of information between the Hub and the clinician. This is designed to enable the patient to self test their full blood count in their home and transmit the data remotely to a clinician for review. In addition to testing their full blood count, the patients can input their temperature and any symptoms they have onto the device. The clinician will then be able to send appropriate instructions back to the patient. The Philips Zodiac system can also send a preprogrammed automated message based on the results of testing.

02

Conditions studied

  • Cancer

Keywords

  • Chemotherapy use
  • Home Monitoring
03

Who can participate

Ages eligible
19 Years to 75 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. Male or female, age > 18.
  2. Able to give informed written consent in the English language.
  3. Diagnosis of cancer and receiving chemotherapy or with a planned chemotherapy start date within 2 weeks of enrolment.
  4. Patients who are able to perform finger prick test to obtain capillary blood.

Exclusion criteria

Exclusion Criteria:

  1. Inability to give informed consent due to mental capacity or language problems.
  2. Patients at risk of bruising or bleeding as a result of their disease or treatment.
  3. Patients at risk of bruising or bleeding due to anticoagulants (heparin or warfarin), aspirin or thrombocytopenia (platelet count \<80).
  4. Patients with diabetes mellitus
  5. Patients with peripheral neuropathy
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
20 participants (estimated)

Study arms

  • Experimental
    Home Monitoring

    All participants will receive a home telemonitoring system which will allow cancer patients receiving chemotherapy to test their blood count at home.

    Device: Home Telemonitoring System (The Zodiac, Philips Health care)

Interventions

  • DeviceHome Telemonitoring System (The Zodiac, Philips Health care)

    Full blood count (FBC) home tele-monitoring system which will allow cancer patients receiving chemotherapy to test their blood count at home (haemoglobin, haematocrit, white cell count and neutrophil count).

05

What researchers measure

Primary outcomes

  1. Capillary Blood Sample

    To achieve a read out result of a full blood count (haemoglobin, haematocrit, white cell count and neutrophil count) from capillary blood obtained by finger prick and analysed in the Philips Zodiac system that varies by no more than 15% from a sample reported by the standard hospital based laboratory analyser for white cell count, haemoglobin and haematocrit using venous blood.

    Time frame: 3 times per week for 6 weeks

Secondary outcomes

  1. Number of variances in neutrophil and haemoglobin

    To measure the number of variances in the neutrophil and haemoglobin values between the Philips Zodiac system and hospital laboratory analyser, which could result in a different clinical decision being made based on the management of patients at risk of neutropenia and anaemia.

    Time frame: 3 times per week for 6 weeks

  2. Usability

    To document the level of satisfaction and feasibility using questionnaires, in the use of the Philips Zodiac system (training, ease of use, performing a blood test and preference for home testing versus hospital testing)

    Time frame: 3 weeks and 6 weeks of use

  3. Performance Evaluation

    The questionnaire will assess the patients response to the flow of information via the server software, i.e. the ability of the Philips Zodiac system to provide the patient with a correct automated message or message from a clinician based on the results of the testing; the ability of patients to receive and understand the system messages; and, the satisfaction of patients with the Philips Zodiac System in terms of training issues, ease of use, performing a blood test, performing quality control tests and preference for home testing versus hospital testing.

    Time frame: 3 times per week for weeks 1-6

06

Study locations

1 site
  • Royal Marsden Hospital
    Belmont, Surrey, United Kingdom
07

Registry details

Key details

Study ID
NCT01436669
Lead sponsor
Philips Healthcare
Collaborators
The Royal Marsden Hospital
Responsible party
Sponsor
First posted
Sep 20, 2011
Start date
Jun 2011
Primary completion
May 2012
Completion
May 2012
Last update
Mar 18, 2021

Study contacts

Nic Kent
study director · Philips Healthcare

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

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